Evidence map›Paper›PMID 28798136›Full record

ArticleDisease models & mechanisms2017

Adipose tissue and metabolic and inflammatory responses to stroke are altered in obese mice.

Michael J Haley, Graham Mullard, Katherine A Hollywood, Garth J Cooper, Warwick B Dunn, Catherine B Lawrence

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Metabolomics of Aerobic Exercise in Chronic Stroke Survivors: A Pilot Study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2019
    Trial
  2. Review
  3. Article
  4. Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Ligature-induced periodontitis induces systemic inflammation but does not alter acute outcome after stroke in mice.International journal of stroke : official journal of the International Stroke Society · 2020
    Article
  12. Review
  13. Revealing the Pharmacological Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  14. Acute high-fat feeding leads to disruptions in glucose homeostasis and worsens stroke outcome.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Michael J HaleyFaculty of Biological, Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, M13 9PT, UK.
Graham MullardCentre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Biological, Medical and Human Sciences, University of Manchester, Manchester, M13 9WL, UK.
Katherine A HollywoodCentre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Biological, Medical and Human Sciences, University of Manchester, Manchester, M13 9WL, UK.
Garth J CooperCentre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Biological, Medical and Human Sciences, University of Manchester, Manchester, M13 9WL, UK.
Warwick B DunnCentre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Biological, Medical and Human Sciences, University of Manchester, Manchester, M13 9WL, UK.
Catherine B LawrenceFaculty of Biological, Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, M13 9PT, UK catherine.lawrence@manchester.ac.uk.ORCID 0000-0002-2372-2968
Manchester Academic Health Science Centre · GBUniversity of Auckland · NZ

Funding

Medical Research Council MR/M009157/1Wellcome Trust
6 · The paper itself

Abstract

Obesity is an independent risk factor for stroke, although several clinical studies have reported that obesity improves stroke outcome. Obesity is hypothesised to aid recovery by protecting against post-stroke catabolism. We therefore assessed whether obese mice had an altered metabolic and inflammatory response to stroke. Obese

Indexed as

Energy MetabolismAdipokinesAdipose TissueAnimalsBiomarkersChromatography, High Pressure LiquidCytokinesDisease Models, AnimalFatty Acids, NonesterifiedInfarction, Middle Cerebral ArteryInflammation MediatorsLipolysisLiverMaleMass SpectrometryMetabolomicsAdipokinesBiomarkersCytokinesFatty Acids, NonesterifiedInflammation MediatorsAdipokinesInflammationLipidsMetabolomicsObesityStroke

Identifiers

PMID28798136
PMCPMC5665457
OpenAlexW2741781578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.