Evidence map›Paper›PMID 28798083›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2017

Stela McLachlan, Kathryn E Page, Seung-Min Lee, Alex Loguinov, Erika Valore, Simon T Hui, Grace Jung, Jie Zhou, Aldons J Lusis, Brie Fuqua and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. The neogenin-hemojuvelin axis in murine liver is crucial for hepcidin expression.American journal of physiology. Gastrointestinal and liver physiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The role of iron metabolism in chronic diseases related to obesity.Molecular medicine (Cambridge, Mass.) · 2022
    Review
  9. Article
  10. Article
  11. Genetic loss ofHaematologica · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Stela McLachlanCentre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom; stela.mclachlan@ed.ac.uk.ORCID http://orcid.org/0000-0003-0480-6143
Kathryn E PageDepartment of Nutritional Science & Toxicology, University of California, Berkeley, California.
Seung-Min LeeDepartment of Food and Nutrition, College of Human Ecology, Yonsei University, Seoul, Korea.
Alex LoguinovDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida.
Erika ValoreDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California; and.
Simon T HuiDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California; and.
Grace JungDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California; and.
Jie ZhouDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida.
Aldons J LusisDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California; and.
Brie FuquaDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California; and.
Tomas GanzDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California; and.
Elizabeta NemethDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California; and.
Chris D VulpeDepartment of Nutritional Science & Toxicology, University of California, Berkeley, California.
University of California, Los Angeles · USUniversity of Florida · USGlasgow Centre for Population Health · GBUniversity of California, Berkeley · USYonsei University · KR

Funding

Systems genomics of metabolic syndrome traitsP01HL028481 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CANTOR, RITA M. · 1985 to 2019
$50.2M
The role of erythroferrone in iron homeostasis and in iron-loading anemiasR01DK065029 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GANZ, TOMAS · 2004 to 2017
$4.9M
Ferroportin Structure and functionR01DK107309 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JORMAKKA, MIKA, MACKENZIE, BRYAN · 2015 to 2019
$3.0M
An integrated molecular approach to understand variation in iron metabolismR01GM083198 · NIGMS · UNIVERSITY OF FLORIDA · PI VULPE, CHRISTOPHER D · 2012 to 2015
$2.7M
Allylsilane Annulation Strategy for Diversity SynthesisF32CA094588 · NCI · HARVARD UNIVERSITY · PI FRANZ, ANNALIESE K · 2002 to 2004
$125k
NCI NIH HHS F32 CA094588NHLBI NIH HHS P01 HL028481NIDDK NIH HHS R01 DK065029NIDDK NIH HHS R01 DK107309NIGMS NIH HHS R01 GM083198
6 · The paper itself

Abstract

Iron homeostasis is tightly regulated, and the peptide hormone hepcidin is considered to be a principal regulator of iron metabolism. Previous studies in a limited number of mouse strains found equivocal sex- and strain-dependent differences in mRNA and serum levels of hepcidin and reported conflicting data on the relationship between hepcidin (

Indexed as

AnimalsDietFemaleHepcidinsIronIron, DietaryMaleMiceMice, Inbred StrainsRNA, MessengerSex CharacteristicsSpecies SpecificityTissue DistributionTransferrinHamp protein, mouseHepcidinsIronIron, DietaryRNA, MessengerTransferrinHamp1 mRNAinbred mouse strainplasma hepcidinsex specifictissue iron

Identifiers

PMID28798083
PMCPMC5792216
OpenAlexW2744687269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.