Evidence map›Paper›PMID 28797330›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

Evolving beta-lactamase epidemiology in Enterobacteriaceae from Italian nationwide surveillance, October 2013: KPC-carbapenemase spreading among outpatients.

Tommaso Giani, Alberto Antonelli, Mariasofia Caltagirone, Carola Mauri, Jessica Nicchi, Fabio Arena, Elisabetta Nucleo, Silvia Bracco, Annalisa Pantosti, AMCLI-CoSA survey participants and 3 more

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Tommaso GianiDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Alberto AntonelliThese authors contributed equally to this work.
Mariasofia CaltagironeDepartment of Clinical, Surgical, Diagnostic, and Paediatric Sciences, Section of Microbiology, University of Pavia, Pavia, Italy.
Carola MauriMicrobiology and Virology Unit, Department of Laboratory Medicine, A. Manzoni Hospital, Lecco, Italy.
Jessica NicchiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Fabio ArenaDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Elisabetta NucleoDepartment of Clinical, Surgical, Diagnostic, and Paediatric Sciences, Section of Microbiology, University of Pavia, Pavia, Italy.
Silvia BraccoMicrobiology and Virology Unit, Department of Laboratory Medicine, A. Manzoni Hospital, Lecco, Italy.
Annalisa PantostiDepartment of Infectious, Parasitic and Immune-Mediated Diseases, Italian National Health Institute, Rome, Italy.
AMCLI-CoSA survey participantsThe AMCLI-CoSA survey participants are listed at the end of the article.
Francesco LuzzaroMicrobiology and Virology Unit, Department of Laboratory Medicine, A. Manzoni Hospital, Lecco, Italy.
Laura PaganiDepartment of Clinical, Surgical, Diagnostic, and Paediatric Sciences, Section of Microbiology, University of Pavia, Pavia, Italy.
Gian Maria RossoliniDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
University of Siena · ITUniversity of Pavia · ITAlessandro Manzoni Hospital · ITUniversity of Florence · ITSchool of the Art Institute of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extended-spectrum beta-lactamases (ESBLs), AmpC-type beta-lactamases (ACBLs) and carbapenemases are among the most important resistance mechanisms in Enterobacteriaceae. This study investigated the presence of these resistance mechanisms in consecutive non-replicate isolates of Escherichia coli (n = 2,352), Klebsiella pneumoniae (n = 697), and Proteus mirabilis (n = 275) from an Italian nationwide cross-sectional survey carried out in October 2013. Overall, 15.3% of isolates were non-susceptible to extended-spectrum cephalosporins but susceptible to carbapenems (ESCR-carbaS), while 4.3% were also non-susceptible to carbapenems (ESCR-carbaR). ESCR-carbaS isolates were contributed by all three species, with higher proportions among isolates from inpatients (20.3%) but remarkable proportions also among those from outpatients (11.1%). Most ESCR-carbaS isolates were ESBL-positive (90.5%), and most of them were contributed by E. coli carrying bla

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCephalosporinsCross-Sectional StudiesEnterobacteriaceae InfectionsEscherichia coliEscherichia coli InfectionsFemaleHumansItalyKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsMolecular EpidemiologyOutpatientsAmpC beta-lactamasesAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCephalosporinscarbapenemaseClass C beta-lactamasesEnterobacteriaceaeepidemiologyESBLoutpatients

Identifiers

PMID28797330
PMCPMC5553057
OpenAlexW2742987555

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.