Evidence map›Paper›PMID 28797328›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

Co-occurrence of colistin-resistance genes mcr-1 and mcr-3 among multidrug-resistant Escherichia coli isolated from cattle, Spain, September 2015.

Marta Hernández, M Rocío Iglesias, David Rodríguez-Lázaro, Alejandro Gallardo, Narciso Quijada, Pedro Miguela-Villoldo, Maria Jorge Campos, Segundo Píriz, Gema López-Orozco, Cristina de Frutos and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The Co-Existence ofAntibiotics (Basel, Switzerland) · 2025
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  5. Molecular epidemiology ofAntimicrobial agents and chemotherapy · 2025
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  6. Identification ofInternational journal of microbiology · 2025
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  7. Article
  8. Article
  9. Article
  10. Co-Existence ofInternational journal of molecular sciences · 2023
    Article
  11. Genomic Surveillance ofAntibiotics (Basel, Switzerland) · 2023
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  12. Plasmid-mediatedAntimicrobial agents and chemotherapy · 2023
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  13. Molecular characterization of multidrug resistantFrontiers in cellular and infection microbiology · 2023
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  14. Article
  15. Prevalence and Population Diversity ofAnimals : an open access journal from MDPI · 2022
    Article
  16. Article
  17. Worldwide Prevalence ofPathogens (Basel, Switzerland) · 2022
    Review
  18. Article
  19. Article
  20. Colistin Resistance Mechanisms in HumanAntibiotics (Basel, Switzerland) · 2022
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Marta HernándezLaboratorio de Biología Molecular y Microbiología, Instituto Tecnológico Agrario de Castilla y León, Valladolid, Spain.
M Rocío IglesiasThese authors contributed equally to the manuscript.
David Rodríguez-LázaroThese authors contributed equally to the manuscript.
Alejandro GallardoDepartamento de Bioquímica, Biología Molecular y Genética, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Narciso QuijadaLaboratorio de Biología Molecular y Microbiología, Instituto Tecnológico Agrario de Castilla y León, Valladolid, Spain.
Pedro Miguela-VilloldoVISAVET Health Surveillance Centre, Universidad Complutense, Madrid, Spain.
Maria Jorge CamposMARE - Marine and Environmental Sciences Centre, Instituto Politécnico de Leiria, Peniche, Portugal.
Segundo PírizDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Gema López-OrozcoSubdirección General de Sanidad e Higiene Animal y Trazabilidad, Ministerio de Agricultura y Pesca, Alimentación y Medio Ambiente, Madrid, Spain.
Cristina de FrutosLaboratorio Central de Veterinaria, Ministerio de Agricultura y Pesca, Alimentación y Medio Ambiente, Algete, Spain.
José Luis SáezSubdirección General de Sanidad e Higiene Animal y Trazabilidad, Ministerio de Agricultura y Pesca, Alimentación y Medio Ambiente, Madrid, Spain.
María Ugarte-RuizVISAVET Health Surveillance Centre, Universidad Complutense, Madrid, Spain.
Lucas DomínguezVISAVET Health Surveillance Centre, Universidad Complutense, Madrid, Spain.
Alberto QuesadaDepartamento de Bioquímica, Biología Molecular y Genética, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Universidad de Extremadura · ESMinisterio de Agricultura, Pesca y Alimentación · ESUniversidad Complutense de Madrid · ESInstituto Tecnológico Agrario de Castilla y León · ESInstituto Politécnico de Leiria · PTUniversidad de Burgos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colistin resistance genes mcr-3 and mcr-1 have been detected in an Escherichia coli isolate from cattle faeces in a Spanish slaughterhouse in 2015. The sequences of both genes hybridised to same plasmid band of ca 250 kb, although colistin resistance was non-mobilisable. The isolate was producing extended-spectrum beta-lactamases and belonged to serotype O9:H10 and sequence type ST533. Here we report an mcr-3 gene detected in Europe following earlier reports from Asia and the United States.

Indexed as

AnimalsAnti-Bacterial Agentsbeta-LactamasesCattleColistinDrug Resistance, BacterialEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFecesMicrobial Sensitivity TestsMolecular TypingPeptidesPolymerase Chain ReactionSentinel SurveillanceAnti-Bacterial Agentsbeta-LactamasesColistinEscherichia coli ProteinsMCR-1 protein, E coliMCR 4 peptidePeptidesantimicrobial resistancebovinecattlecolistinEscherichia colimcr-1mcr-3

Identifiers

PMID28797328
PMCPMC5553059
OpenAlexW2742755567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.