Trial reportJournal of the International Neuropsychological Society : JINS2018
Self-perceived Difficulties in Everyday Function Precede Cognitive Decline among Older Adults in the ACTIVE Study.
Trial report in Journal of the International Neuropsychological Society : JINS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- The impact of behavioral interventions on cognitive function in healthy older adults: A systematic review.Ageing research reviews · 2019Pooled it
- Prediction and mediation analysis for treatment responses to combined cognitive and physical training for older adults.Scientific reports · 2024Trial
- Effects of creative expression therapy for older adults with mild cognitive impairment at risk of Alzheimer's disease: a randomized controlled clinical trial.Clinical interventions in aging · 2018Trial
- Digital tools for cognitive healthcare: Exploring perceptions of an everyday function app among midlife and older adults.Applied psychology. Health and well-being · 2026Article
- Digital neuropsychological assessment-Part 2: Relations with cardiovascular risk and informant ratings of neurocognitive decline, functional disabilities, and psychiatric symptoms.Journal of Alzheimer's disease : JAD · 2026Article
- Childhood maltreatment and cognitive functioning from young adulthood to late midlife: A prospective study.Neuropsychology · 2026Article
- Older adults' views of passive smartphone monitoring for dementia risk: a multi-method analysis.Innovation in aging · 2026Article
- Precision neurocognition: An emerging diagnostic paradigm leveraging digital cognitive assessment technology.Journal of Alzheimer's disease : JAD · 2025Review
- The impact of tract- and county-level segregation on 10-year cognitive and everyday functioning outcomes of Black/African American older adults in the ACTIVE study.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2025Article
- Social factors associated with everyday functioning in older Black adults.Journal of the International Neuropsychological Society : JINS · 2025Article
- Triboelectric nanogenerators for neural data interpretation: bridging multi-sensing interfaces with neuromorphic and deep learning paradigms.Frontiers in computational neuroscience · 2025Review
- Association between ranolazine therapy and cognitive decline in elderly patients with ischemic heart disease.Frontiers in pharmacology · 2025Article
- Differences in Daily Physical Activity by Alzheimer's Risk Markers Among Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Contributions of loneliness to cognitive impairment and dementia in older adults are independent of other risk factors and Alzheimer's pathology: a narrative review.Frontiers in human neuroscience · 2024Review
- Dysexecutive difficulty and subtle everyday functional disabilities: the digital Trail Making Test.Frontiers in neurology · 2024Article
- Social Isolation and Loneliness in a Population Study of Cognitive Impairment: The MYHAT Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023Article
- Validation of the Short Form of Korean-Everyday Cognition (K-ECog).Journal of Korean medical science · 2023Article
- Subjective Cognitive Decline Is Associated With Lower Baseline Cognition and Increased Rate of Cognitive Decline.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- Correlating continuously captured home-based digital biomarkers of daily function with postmortem neurodegenerative neuropathology.PloS one · 2023Article
- Original research: longitudinal evaluation of cognitively demanding daily function using performance-based functional assessment highlights heterogeneous trajectories in cognitive and functional abilities in people with Parkinson's disease.Frontiers in neuroscience · 2023Article
Corrections and comments
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Authors and funding
11 authors at 9 institutions in 1 country.
Funding
Abstract
objectivesCareful characterization of how functional decline co-evolves with cognitive decline in older adults has yet to be well described. Most models of neurodegenerative disease postulate that cognitive decline predates and potentially leads to declines in everyday functional abilities; however, there is mounting evidence that subtle decline in instrumental activities of daily living (IADLs) may be detectable in older individuals who are still cognitively normal.
methodsThe present study examines how the relationship between change in cognition and change in IADLs are best characterized among older adults who participated in the ACTIVE trial. Neuropsychological and IADL data were analyzed for 2802 older adults who were cognitively normal at study baseline and followed for up to 10 years.
resultsFindings demonstrate that subtle, self-perceived difficulties in performing IADLs preceded and predicted subsequent declines on cognitive tests of memory, reasoning, and speed of processing.
conclusionsFindings are consistent with a growing body of literature suggesting that subjective changes in everyday abilities can be associated with more precipitous decline on objective cognitive measures and the development of mild cognitive impairment and dementia. (JINS, 2018, 24, 104-112).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.