ReviewParasites & vectors2017
Host immune responses to the itch mite, Sarcoptes scabiei, in humans.
Review in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 142 citations in OpenAlex.
- Evidence underscoring immunological and clinical pathological changes associated with Sarcoptes scabiei infection: synthesis and meta-analysis.BMC infectious diseases · 2022Pooled it
- The Rash That Will Not Go Away.Clinical pediatrics · 2026Article
- The Impact of Steroid Use on Scabies Treatment: An Evaluation of Clinical Severity, Parasite Burden, and the Validity of a Novel Scoring System.International journal of dermatology · 2026Article
- Integrated in vitro and in vivo evaluation of ivermectin hydrogel formulation for management of scabies with pharmacological assessment.Scientific reports · 2026Article
- Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Article
- An Unexpected Dupilumab Reaction.Cureus · 2026Article
- Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission.bioRxiv : the preprint server for biology · 2025Article
- Antiparasitic efficacy of geraniol from Apiaceae family in scabies treatment.Scientific reports · 2025Article
- Initial stage of crusted scabies and possible diagnostic characteristics: A case series.Parasitology · 2025Review
- Effects of probiotic supplementation on clinicopathological alterations in Barki sheep with Mange.Open veterinary journal · 2025Article
- Genomics reveal local skin immune response key to control sarcoptic mange in Iberian ibex (Capra pyrenaica).BMC genomics · 2024Article
- Resurgence of scabies in Italy: The new life of an old disease.Parasite epidemiology and control · 2024Article
- Scabies.Nature reviews. Disease primers · 2024Review
- Clinical practice guidelines for the diagnosis and treatment of scabies in Korea: Part 2. Treatment and prevention - a secondary publication.Ewha medical journal · 2024Article
- Exploring Blood Cell Count-Derived Ratios as Practical Diagnostic Tools for Scabies in Vulnerable Populations.Journal of personalized medicine · 2024Article
- Scabies: Immunopathogenesis and pathological changes.Parasitology research · 2024Review
- Case report of crusted scabies, brief review of its pathophysiology and latest data.AME case reports · 2024Article
- The Itchy Truth About Scabies: A Case of Asymptomatic Carrier Transmission and Treatment Failure.Cureus · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scabies is a parasitic disease due to infestation of skin by the burrowing mite Sarcoptes scabiei. Scabies is a major public health problem and endemic in resource poor communities worldwide affecting over 100 million people. Associated bacterial infections cause substantial morbidity, and in severe cases can lead to renal and cardiac diseases. Mite infestation of the skin causes localised cutaneous inflammation, pruritus, skin lesions, and allergic and inflammatory responses are mounted by the host against the mite and its products. Our current understanding of the immune and inflammatory responses associated with the clinical manifestations in scabies is far outweighed by the significant global impact of the disease. This review aims to provide a better understanding of human immune responses to S. scabiei in ordinary and crusted scabies phenotypes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.