ArticlePediatric rheumatology online journal2017
Joint cartilage thickness and automated determination of bone age and bone health in juvenile idiopathic arthritis.
Article in Pediatric rheumatology online journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- No radiographic wrist damage after treatment to target in recent-onset juvenile idiopathic arthritis.Pediatric rheumatology online journal · 2019Trial
- Longitudinal course of bone health from infancy to mid-adulthood in preterm and term-born individuals.Scientific reports · 2025Article
- The assessment of bone health in children with juvenile idiopathic arthritis; comparison of different imaging-based methods.Pediatric rheumatology online journal · 2024Article
- Diagnostic and prognostic role of synovial tissue analysis in juvenile idiopathic arthritis: a monocentric study.RMD open · 2023Article
- Juvenile idiopathic arthritis: from aetiopathogenesis to therapeutic approaches.Pediatric rheumatology online journal · 2021Review
- Traditional and New Methods of Bone Age Assessment-An OverviewJournal of clinical research in pediatric endocrinology · 2021Article
- Important Tools for Use by Pediatric Endocrinologists in the Assessment of Short StatureJournal of clinical research in pediatric endocrinology · 2021Review
- Association of Circulating COMP and YKL-40 as Markers of Metabolic Changes of Cartilage with Adipocytokines in Juvenile Idiopathic Arthritis.Metabolites · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBoneXpert is an automated method to calculate bone maturation and bone health index (BHI) in children with juvenile idiopathic arthritis (JIA). Cartilage thickness can also be seen as an indicator for bone health and arthritis damage. The objective of this study was to evaluate the relation between cartilage thickness, bone maturation and bone health in patients with JIA.
methodsPatients with JIA diagnosed according ILAR criteria included in a previous ultrasonography (US) study were eligible if hand radiographs were taken at the same time as the US examination. Of the 95 patients 67 met the inclusion criteria.
resultsDecreased cartilage thickness was seen in 27% of the examined joints. Decreased BHI was seen in half of the JIA patient, and delayed bone maturation was seen in 33% of patients. A combination of decreased BHI and bone age was seen in 1 out of 5 JIA patients. Decreased cartilage thickness in the knee, wrist and MCP joint was negatively correlated with delayed bone maturation but not with bone health index.
conclusionDelayed bone maturation and decreased BHI were not related to a thinner cartilage, but a thicker cartilage. No relation with JADAS 10 was found. The rheumatologist should remain aware of delayed bone maturation and BHI in JIA patients with cartilage changes, even in the biologic era.
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Registered trials
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