ArticleBMC genomics2017
Succinyl-proteome profiling of Dendrobium officinale, an important traditional Chinese orchid herb, revealed involvement of succinylation in the glycolysis pathway.
Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 40 citations in OpenAlex.
- Protein post-translational modification by lysine succinylation: Biochemistry, biological implications, and therapeutic opportunities.Genes & diseases · 2023Review
- Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.).BMC plant biology · 2022Article
- Article
- Refined polysaccharide fromFrontiers in immunology · 2022Article
- Dynamic Responses of Barley Root Succinyl-Proteome to Short-Term Phosphate Starvation and Recovery.Frontiers in plant science · 2021Article
- Research Advances in Multi-Omics on the Traditional Chinese HerbFrontiers in plant science · 2021Review
- Development, Identification, and Application of a Germplasm Specific SCAR Marker forFrontiers in plant science · 2021Article
- The phosphoproteomic responses of duck (Cairna moschata) to classical/novel duck reovirus infections in the spleen tissue.Scientific reports · 2020Article
- Detection of superoxide dismutase (Cu-Zn) isoenzymes in leaves and pseudobulbs ofBiochemistry and biophysics reports · 2020Article
- Systematic identification and comparative analysis of lysine succinylation between the green and white parts of chimeric leaves of Ananas comosus var. bracteatus.BMC genomics · 2020Article
- SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation.The EMBO journal · 2020Article
- Comprehensive Succinylome Profiling Reveals the Pivotal Role of Lysine Succinylation in Energy Metabolism and Quorum Sensing ofFrontiers in microbiology · 2020Article
- Comparative metabolomic analyses ofPeerJ · 2020Article
- First Succinylome Profiling ofFrontiers in cellular and infection microbiology · 2020Article
- Global Proteomic Analysis Reveals Widespread Lysine Succinylation in Rice Seedlings.International journal of molecular sciences · 2019Article
- Quantitative succinyl-proteome profiling of Chinese hickory (Carya cathayensis) during the grafting process.BMC plant biology · 2019Article
- Succinyl-proteome profiling of Pyricularia oryzae, a devastating phytopathogenic fungus that causes rice blast disease.Scientific reports · 2019Article
- Review
- Global analysis of lysine succinylation in patchouli plant leaves.Horticulture research · 2019Article
- Coupling Krebs cycle metabolites to signalling in immunity and cancer.Nature metabolism · 2019Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLysine succinylation is a ubiquitous and important protein post-translational modification in various eukaryotic and prokaryotic cells. However, its functions in Dendrobium officinale, an important traditional Chinese orchid herb with high polysaccharide contents, are largely unknown.
resultsIn our study, LC-MS/MS was used to identify the peptides that were enriched by immune-purification with a high-efficiency succinyl-lysine antibody. In total, 314 lysine succinylation sites in 207 proteins were identified. A gene ontology analysis showed that these proteins are associated with a wide range of cellular functions, from metabolic processes to stimuli responses. Moreover, two types of conserved succinylation motifs, '***K
conclusionsOur results provide the first comprehensive view of the succinylome of D. officinale and may accelerate future biological investigations of succinylation in the synthesis of polysaccharides, which are major active ingredients.
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