Evidence map›Paper›PMID 28796058›Full record

Observational studyMedicine2017

Posttransplantation anemia in kidney transplant recipients: A retrospective cohort study.

Anat Gafter-Gvili, Irit Ayalon-Dangur, Lisa Cooper, Tzippy Shochat, Ruth Rahamimov, Uzi Gafter, Eytan Mor, Alon Grossman

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Anemia after kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2023
    Article
  9. Postrenal transplant anemia and its effects on patients and graft outcomes: Seven years follow-up.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Post-Transplantation Early Blood Transfusion and Kidney Allograft Outcomes: A Single-Center Observational Study.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Observational
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anat Gafter-GviliDepartment of Medicine A, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Department of Medicine E, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel Department of Geriatrics, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel Bio-Statistical Unit, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel Department of Nephrology and Hypertension, Rabin Medical Center, Petah Tikva, Israel Department of Transplantation, Rabin Medical Center, Beilinson Campus, Israel.
Irit Ayalon-Dangur
Lisa Cooper
Tzippy Shochat
Ruth Rahamimov
Uzi Gafter
Eytan Mor
Alon Grossman
Rabin Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to assess the frequency and predictors of early and late posttransplantation anemia (PTA). In addition, we aimed to assess the outcomes of patients with anemia and to assess the impact of anemia on mortality, graft function, and graft failure.Patients who underwent kidney transplantation in a single center during a 4-year period were included. Predictors associated with the development of anemia at 6 months (early PTA) or 2 years (late PTA) were evaluated in a univariate and multivariate analyses. The effects of anemia and other variables on mortality and graft function were assessed.A total of 266 kidney transplant recipients were included. The prevalence of PTA at 6 months (early PTA) was 51.3% and at 2 years (late PTA) was 36.6%. Female sex was significantly associated with early PTA. Patients with early PTA proceeded to late PTA. Patients with both early and late PTA had a higher mortality rate at 4 years compared to patients without anemia. On multivariable analysis, lower Hb at 2 years posttransplantation (hazard ratio [HR] 0.716, 95% confidence intervals [CI] 0.541-0.948, for every increment of 1 g/dL) was significantly associated with mortality. Patients with late PTA suffered a decline in eGFR compared to patients without anemia (P = .026). Furthermore, a lower Hb at 2 years posttransplantation was also associated with graft failure (HR 0.775, 95% CI 0.619-0.969, for every increment of 1 g/dL).Post-transplantation anemia is significantly associated with late mortality, with a decline in graft function and with an increased incidence of graft failure.

Indexed as

AdultAnemiaFemaleGraft RejectionHemoglobinsHumansKidney TransplantationMaleMiddle AgedPostoperative ComplicationsPrevalenceRetrospective StudiesRisk FactorsSex FactorsTime FactorsTransplant RecipientsHemoglobins

Identifiers

PMID28796058
PMCPMC5556224
OpenAlexW2745010101

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.