ArticleSurgery today2018
The mean corpuscular volume as a prognostic factor for colorectal cancer.
Article in Surgery today, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Prognostic factors for 5 year relapse-free survivors following curative resection for stage II/III colorectal cancer.Surgery today · 2026Article
- Mean Corpuscular Volume as a Prognostic Marker in Patients with Non-Small Cell Lung Cancer Undergoing Surgical Resection: A Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Sequential changes in conditional survival of patients following surgical resection of colorectal cancer and indicators for follow-up beyond 5 years.International journal of clinical oncology · 2026Article
- Significance of preoperative mean corpuscular volume in patients with stage II/III colorectal cancer and anemia.International journal of clinical oncology · 2025Article
- Complex association of mean corpuscular volume and outcomes in patients with aplastic anemia treated with cyclosporine A plus androgen or cyclosporine A alone.Clinical and experimental medicine · 2025Article
- Ribonucleotide-diphosphate reductase subunit M2 (RRM2) expression and colorectal cancer invasiveness: a potential prognostic biomarker.Molecular biology reports · 2025Article
- Prognostic Significance of Modified Shine and Lal Index in Patients with Non-Small Cell Lung Cancer Undergoing Surgical Resection.Biomedicines · 2025Article
- The longevity factor spermidine is part of a highly heritable complex erythrocyte phenotype associated with longevity.Aging cell · 2024Article
- Prognostic value of pre-operative mean corpuscular volume (MCV) in colorectal cancer.Irish journal of medical science · 2024Article
- Prognostic value of neutrophil-to-lymphocyte ratio (NLR) and platelet-neutrophil (PN) index in locally advanced rectal cancer patients: a retrospective cohort study.Annals of medicine and surgery (2012) · 2024Article
- Mean corpuscular volume as a prognostic factor for 30-day mortality in major trauma patients: a retrospective cohort study.Scientific reports · 2024Article
- Efficacy and safety of laparoscopicWorld journal of clinical cases · 2023Article
- Clinical significance of the histopathological metastatic largest lymph node size in colorectal cancer patients.Frontiers in oncology · 2023Article
- Clinical significance of mean corpuscular volume as a prognostic indicator of radiotherapy for locally advanced lung cancer: a retrospective cohort study.Journal of thoracic disease · 2022Article
- Article
- Age-related changes in mean corpuscular volumes in patients without anaemia: An analysis of large-volume data from a single institute.Journal of cellular and molecular medicine · 2022Article
- Optimal cutoff value of preoperative CEA and CA19-9 for prognostic significance in patients with stage II/III colon cancer.Langenbeck's archives of surgery · 2021Article
- Significant association between the preoperative erythrocyte mean corpuscular volume and infectious complications after pancreaticoduodenectomy.Surgery today · 2021Article
- Mean Corpuscular Volume as a Prognostic Factor for Patients With Habitual Alcohol or Tobacco Use After Esophagectomy.Frontiers in oncology · 2021Article
- High Red Cell Distribution Width Independently Predicts Adverse Survival in Patients with Newly Diagnosed Skull Base Chordoma.OncoTargets and therapy · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
purposeThe aim of the present study was to identify the factors investigated during routine blood examinations which can predict the disease outcome independent of the tumor stage.
methodsData from 1174 patients with stage I, II, and III CRC who underwent R0 resection were included. We investigated the correlations between the preoperative routine blood examination data, and clinicopathological factors, and disease-free survival (DFS) using univariate and multivariate analyses.
resultsThe univariate analysis showed that tumor location, tumor stage, CRP, serum albumin, creatine kinase, neutrophil-to-lymphocyte ratio, red blood cell count, mean corpuscular volume (MCV), and the administration of postoperative adjuvant chemotherapy were significantly correlated with the DFS. The multivariate analysis of the factors associated with the DFS showed that stage and MCV were significant factors; an MCV of <80 fL was associated with a superior DFS in comparison to an MCV of 80-100 fL (hazard ratio: 0.31, 95% confidence interval: 0.13-0.61, p = 0.0003). The DFS in patients with an MCV of <80 fL was superior to that in patients with an MCV of ≥80 fL, irrespective of whether the patients underwent postoperative adjuvant chemotherapy.
conclusionMCV was a prognostic factor for the DFS, independent of the tumor stage, in CRC patients who underwent R0 resection.
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