ReviewBurns & trauma2017
Sepsis in the burn patient: a different problem than sepsis in the general population.
Review in Burns & trauma, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 1 synthesis or guideline pooled it, 182 citations in OpenAlex.
- CNS-Spleen Axis - a Close Interplay in Mediating Inflammatory Responses in Burn Patients and a Key to Novel Burn Therapeutics.Frontiers in immunology · 2021Pooled it
- Multi-Organ Failure in Adult Patients Admitted to Intensive Care with Severe Burns-A Retrospective Cohort Study.European burn journal · 2026Article
- Pancreatic Stone Protein in Burns: Clinical Value of Bedside Testing-A Prospective Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Serious Infections in Burn-Injured Adults: A Retrospective Single-Center Study from 1997 to 2023.Journal of burn care & research : official publication of the American Burn Association · 2026Article
- Decoy receptor 3 as a diagnostic marker for sepsis: a meta-analysis.Intensive care medicine experimental · 2026Review
- Target degradation of CASPASE-1 for alleviation of inflammation in sepsisActa pharmaceutica Sinica. B · 2026Article
- Challenges in Antimicrobial Treatment and Antimicrobial Stewardship in Hospital-Acquired Infections in Adult Burn Patients.European burn journal · 2026Review
- A Novel Digital Phenotype for Burn Sepsis: Leveraging Electronic Health Record Data and Natural Language Processing to Improve Case Definition.Applied clinical informatics · 2026Article
- Burn Infections and Sepsis: Challenges and Future Prospects of Antibacterial Therapy.Antibiotics (Basel, Switzerland) · 2026Review
- A Scoping Review of Fluorescence Imaging: A Promising New Technology for Bacterial Detection in Burn Wounds.Journal of burn care & research : official publication of the American Burn Association · 2026Article
- Streamlined machine learning model for early sepsis risk prediction in burn patients.NPJ digital medicine · 2025Article
- A Prospective Observational Study to Determine the Efficacy of a Theatre Prioritisation Tool in Optimal Utilisation of Limited Theatre Time for Deep Burn Injury in a Resource-Restricted Setting.European burn journal · 2025Article
- Pediatric burns in low-income countries: An example from Somalia.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Observational
- Sepsis in burn care: incidence and outcomes.Military Medical Research · 2025Article
- Perioperative lactate levels as prognostic indicators in patients undergoing early excision and grafting for extensive burns.BMC surgery · 2025Article
- The relationship between respiratory tract infections caused by toxin-producing bacteria in burn patients during COVID-19: pathogenesis, diagnostics and novel therapies.Journal of medical microbiology · 2025Review
- Persistent inflammation, immunosuppression, and catabolism syndrome and sepsis in pediatric burns.Burns : journal of the International Society for Burn Injuries · 2025Article
- Early appropriate therapy with polymyxin B reduces the mortality in burn sepsis caused by carbapenem-resistant gram-negative bacteria: a retrospective analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Metabolic and Hormonal Changes in Pediatric Burn Patients: Mechanisms, Evidence, and Care Strategies.European burn journal · 2025Review
- Insights into bloodstream infections in South African paediatric burn patients: implications for antimicrobial stewardship.BMC infectious diseases · 2025Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sepsis has recently been defined as "life-threatening organ dysfunction caused by a dysregulated host response to infection". A great amount of effort has been made to develop early treatments for sepsis through the Surviving Sepsis Campaign. There are similar but slightly different recommendations for the treatment of sepsis in the pediatric population. These international efforts have led to earlier diagnosis and treatments for sepsis that have led to improvements in survival. Sepsis is also the leading cause of death in the burn patient but most clinical sepsis studies have excluded burns. The reason for the exclusion is that the sepsis found in burn patients is different than that of the general population. The early treatment strategies, such as those directed by the Surviving Sepsis Campaign, focus on patients presenting to hospitals with recent signs of infection. Burn patients lose their primary barrier to infection, the skin, and thus the risk of infection persists as long as that barrier is absent. Efforts have been made to define sepsis, septic shock and infection in the burn population but there is constant need for revisions. One focus of this review is to discuss the differences in burn sepsis versus sepsis of the general population. Children often have profound responses to sepsis but can also make remarkable recoveries. This review will also explore problems specific to pediatric burns. The treatment of burns requires a continuous vigilance to watch for the subtle early signs of sepsis and then expeditious initiation of aggressive therapy. Strategies covering optimal management of pediatric burn sepsis will also be summarized.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.