Evidence map›Paper›PMID 28794898›Full record

ArticleClinical hypertension2017

A multicenter cohort study of primary hypertension in Korea: study design and interim analysis of the Korean registry of target organ damage in hypertension (KorHR).

Suk-Won Choi, Seong Woo Han, Jong Sun Ok, Byung-Su Yoo, Mi-Seung Shin, Sung Ha Park, Kyu-Hyung Ryu

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Clinical hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01861080 (Observational Study of Clinical Characteristics and Prognostic Factors of Korean Hypertensives), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01861080 completednot on this map

Observational Study of Clinical Characteristics and Prognostic Factors of Korean Hypertensives

Typeobservational_patient_registrySponsorDongtan Sacred Heart HospitalRan2012 to 2025Enrolled3,000ConditionsHypertension
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Ambulatory blood pressure monitoring profiles in Asia.Journal of clinical hypertension (Greenwich, Conn.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Suk-Won ChoiDivision of Cardiology, Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University, 7 Keunjaebong-Gil, Hwaseong, Gyeonggido 18450 South Korea.
Seong Woo HanDivision of Cardiology, Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University, 7 Keunjaebong-Gil, Hwaseong, Gyeonggido 18450 South Korea.
Jong Sun OkDivision of Cardiology, Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University, 7 Keunjaebong-Gil, Hwaseong, Gyeonggido 18450 South Korea.
Byung-Su YooDivision of Cardiology, Department of Internal Medicine, Yonsei University Wonju Severance Christian Hospital, Wonju, South Korea.
Mi-Seung ShinDivision of Cardiology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea.
Sung Ha ParkDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Seoul, South Korea.
Kyu-Hyung RyuDivision of Cardiology, Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University, 7 Keunjaebong-Gil, Hwaseong, Gyeonggido 18450 South Korea.
Hallym University Dongtan Sacred Heart Hospital · KRGachon University Gil Medical Center · KRSeverance Hospital · KRWonju Severance Christian Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Korean Registry of Target Organ Damage in Hypertension aims to evaluate the clinical characteristics and prevalence of subclinical target organ damage in Korean hypertensive patients.

methodThis is a prospective, observational, multicenter cohort study in which 23 university hospitals participated. Since May 2013, we have enrolled 1,318 consecutive hypertensive patients without known cardiovascular disease who met the following inclusion criteria: 1) age older than 30 years and 2) the first visit to the participating hospitals was within the last 5 years.

resultsThe mean age was 52 ± 12 years; 62.1% were male, and 41.3% were incident hypertensives. Patients with diabetes mellitus accounted for 7.8% of the population and 43.8% had hyperlipidemia or were on statins at baseline. The mean office blood pressures were 152 ± 20/96 ± 14 mmHg for incident hypertensive patients and 129 ± 13/78 ± 10 mmHg for patients on treatment. Patients with electrocardiographic and echocardiographic left ventricular hypertrophy accounted for 18.9 and 25.6%, respectively. The mean brachial-ankle pulse wave velocity (PWV) was 1564 ± 293 m/s and 19.5% had PWV values of more than 1750 cm/s. Patients with microalbuminuria and chronic kidney disease accounted for 21 and 4%, respectively. The first prescribed class of antihypertensive medications was angiotensin converting enzyme inhibitors in 2.9%, angiotensin receptor blockers (ARBs) in 57.5%, diuretics in 7.6%, calcium channel blockers (CCBs) in 61.0%, beta blockers in 17.3%, and fixed dose combination pill in 27.8%.

conclusionOur interim analysis shows that subclinical target organ damage in hypertension is considerably present for incident or treated hypertensive patients. CCBs and ARBs were the most commonly prescribed classes of antihypertensive medications and fixed dose combination pills were actively used in Korea.

trial registrationNCT01861080. Registered 16 May 2013.

Indexed as

HypertensionTarget organ damage

Identifiers

PMID28794898
PMCPMC5540578
OpenAlexW2705603464

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.