ArticleBiomicrofluidics2017
Rapid, chemical-free breaking of microfluidic emulsions with a hand-held antistatic gun.
Article in Biomicrofluidics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Optimization and Parallelization of Sorting by Interfacial Tension (SIFT) for High-Throughput Metabolic Cell Sorting.Micromachines · 2026Article
- Parallelized droplet microfluidic mechanoporation enables robust and clogging-resistant intracellular gene delivery.Microsystems & nanoengineering · 2026Article
- High-fidelity bioassembly of organoids and spheroids using inertial droplet microfluidics for precision oncology and tumor microenvironment modeling.Microsystems & nanoengineering · 2026Article
- Compartmentalized Suspension Array for the Isothermal, Digital, and Multiplex Detection of microRNAs.Journal of the American Chemical Society · 2025Article
- Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells.Nature biotechnology · 2025Article
- Stepwise isolation of diverse metabolic cell populations using sorting by interfacial tension (SIFT).Lab on a chip · 2025Article
- Robust Double Emulsions for Multicolor Fluorescence-Activated Cell Sorting.Analytical chemistry · 2024Article
- Enhancing single-cell encapsulation in droplet microfluidics with fine-tunable on-chip sample enrichment.Microsystems & nanoengineering · 2024Article
- Formation of Giant Unilamellar Vesicles Assisted by Fluorinated Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Water-in-oil droplet-mediated method for detecting and isolating infectious bacteriophage particles via fluorescent staining.Frontiers in microbiology · 2023Article
- A Portable, Negative-Pressure Actuated, Dynamically Tunable Microfluidic Droplet Generator.Micromachines · 2022Article
- Rapid tissue prototyping with micro-organospheres.Stem cell reports · 2022Article
- Droplet Microfluidic Technology for the Early and Label-Free Isolation of Highly-Glycolytic, Activated T-Cells.Micromachines · 2022Article
- Characterizing cell interactions at scale with made-to-order droplet ensembles (MODEs).Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Hydrogels for Single-Cell Microgel Production: Recent Advances and Applications.Frontiers in bioengineering and biotechnology · 2022Review
- Emerging microfluidic technologies for microbiome research.Frontiers in microbiology · 2022Review
- Versatile Tool for Droplet Generation in Standard Reaction Tubes by Centrifugal Step Emulsification.Molecules (Basel, Switzerland) · 2020Article
- Monitoring and external control of pH in microfluidic droplets during microbial culturing.Microbial cell factories · 2020Article
- Double-exclusive liquid repellency (double-ELR): an enabling technology for rare phenotype analysis.Lab on a chip · 2018Article
- An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing.Journal of visualized experiments : JoVE · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Droplet microfluidics can form and process millions of picoliter droplets with speed and ease, allowing the execution of huge numbers of biological reactions for high-throughput studies. However, at the conclusion of most experiments, the emulsions must be broken to recover and analyze their contents. This is usually achieved with demulsifiers, like perfluorooctanol and chloroform, which can interfere with downstream reactions and harm cells. Here, we describe a simple approach to rapidly and efficiently break microfluidic emulsions, which requires no chemicals. Our method allows one-pot multi-step reactions, making it useful for large scale automated processing of reactions requiring demulsification. Using a hand-held antistatic gun, we pulse emulsions with the electric field, coalescing ∼100
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.