Evidence map›Paper›PMID 28794551›Full record

ArticleIndian journal of dermatology

Efficacy and Safety of Terbinafine 500 mg Once Daily in Patients with Dermatophytosis.

P Ravindra Babu, A J S Pravin, Gaurav Deshmukh, Dhiraj Dhoot, Aniket Samant, Bhavesh Kotak

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05119712 (Terbinafine Treatment of Axial Spondyloarthropathy), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05119712 early_phase1withdrawnnot on this map

Terbinafine Treatment of Axial Spondyloarthropathy

TypeinterventionalSponsorOregon Health and Science UniversityRan2021 to 2024Enrolled0ConditionsAnkylosing Spondylitis, Axial Spondyloarthritis, Psoriatic Spondylitis, Spondylitis Secondary to Inflammatory Bowel DiseaseArmsTerbinafine Tablets, Laboratory Testing
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Correlation ofAntimicrobial agents and chemotherapy · 2018
    Trial
  3. Trial
  4. Article
  5. Trichophyton indotineae: Epidemiology, antifungal resistance and antifungal stewardship strategies.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Review
  6. Journal of clinical medicine · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

P Ravindra BabuConsultant Dermatologist, Raga Skin Care, Bengaluru, Karnataka, India.
A J S PravinDepartment of Dermatology and Venerology, Kanyakumari Government Medical College, Nagercoil, Tamil Nadu, India.
Gaurav DeshmukhMedical Services Glenmark Pharmaceuticals, Mumbai, Maharashtra, India.
Dhiraj DhootMedical Services Glenmark Pharmaceuticals, Mumbai, Maharashtra, India.
Aniket SamantMedical Services Glenmark Pharmaceuticals, Mumbai, Maharashtra, India.
Bhavesh KotakMedical Services Glenmark Pharmaceuticals, Mumbai, Maharashtra, India.
Glenmark Pharmaceuticals (India) · INKanyakumari Government Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDermatophytosis are the most common fungal infections globally. Terbinafine is considered to have good potency against dermatophytes, but resistance to terbinafine is on the rise.

objectiveThe objective of this study was to evaluate the efficacy and safety of terbinafine 500 mg given once daily in treatment of patients with superficial dermatophytosis. MATERIALS AND

methodsIt was a retrospective questionnaire-based survey. Each doctor was given survey questionnaire booklet containing survey forms. Clinical response was graded according to the improvement in the affected lesion. Mycological cure was defined as negative microscopy under potassium hydroxide examination and a negative culture in Sabouraud's dextrose agar. Patients were divided into three groups depending on the duration of therapy, Group A - terbinafine 500 mg for 2 weeks, Group B - terbinafine 500 mg for 4 weeks, and Group C - terbinafine 500 mg for 6 weeks.

resultsTotal 50 doctors completed the survey involving 440 patients. In Group A, out of 194 patients, 87% (

conclusionOur survey indicates that terbinafine in a dose of 500 mg given once daily was efficacious and safe in the treatment of patients with dermatophytosis.

Indexed as

Antifungal resistancedermatophytosisterbinafine

Identifiers

PMID28794551
PMCPMC5527721
OpenAlexW2737550589

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.