ArticleIndian journal of anaesthesia2017
Retrospective analysis of post-operative coagulopathy after major hepatic resection at a tertiary care centre in Northern India.
Article in Indian journal of anaesthesia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Effectiveness of prothrombin complex concentrate for the treatment of bleeding: A systematic review and meta-analysis.Journal of thrombosis and haemostasis : JTH · 2020Pooled it
- Failure of preoperative data to accurately predict which patients undergoing major hepatic surgery will develop postoperative coagulation disturbances: a single-hospital retrospective cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Article
- The effectiveness and outcomes of epidural analgesia in patients undergoing open liver resection: a propensity score matching analysis.BMC anesthesiology · 2024Observational
- Abnormal coagulation after hepatectomy in patients with normal preoperative coagulation function.BMC surgery · 2024Article
- Long-term effect of anesthesia choice on patients with hepatocellular carcinoma undergoing open liver resection.Frontiers in oncology · 2022Review
- Hypercoagulability on thromboelastography after living donor hepatectomy-The true side of the coin.Indian journal of anaesthesia · 2021Article
- Metalloproteinase expression after desflurane preconditioning in hepatectomies: A randomized clinical trial.World journal of hepatology · 2020Article
- Benefits of N-acetylcysteine on liver functions in living donor hepatectomy.Indian journal of anaesthesia · 2020Article
- The Effect of Transversus Abdominis Plane Block for Analgesia in Patients Undergoing Liver Transplantation: A Systematic Review and Meta-Analysis.Turkish journal of anaesthesiology and reanimation · 2019Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsHepatic resection is a major surgery associated with intraoperative massive fluid shifts, blood loss, haemodynamic instability and risk of development of post-hepatectomy liver failure. Hepatic resection predisposes the patient to coagulopathy as well as venous thrombosis. However, due to the development of deranged coagulation profile post-operatively, there is a dilemma in starting thromboprophylaxis. Our aim in this study was to determine the incidence of coagulopathy in patients undergoing major hepatectomy.
methodsIn this retrospective study, we included 86 patients who had undergone major hepatectomy between January 2010 and December 2015 at our centre. Intraoperatively, we noted the number of liver segments resected, details of epidural catheter insertion, estimated blood loss, transfusion requirement and need for mechanical ventilation post-operatively. Trends of international normalised ratio (INR) and platelet values were recorded until post-operative day 5.
resultsOf the 86 patients, 6 (7%) had an abnormal coagulation profile pre-operatively and 39 (45.34%) patients developed a derangement in their coagulation profile on 1
conclusionsThe incidence of post-operative coagulopathy in our patients who underwent major liver resection was 45.34%. Epidural catheters could be removed safely without transfusion between POD 5 and 7. There was no incidence of venous thrombosis or thromboembolism.
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