ArticleScientific reports2017
Evidence of Energetic Optimization during Adaptation Differs for Metabolic, Mechanical, and Perceptual Estimates of Energetic Cost.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03916562 (Toward a Mechanistic Understanding of Optimization Principles Underlying Hemiparetic Gait), which is not on this map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Toward a Mechanistic Understanding of Optimization Principles Underlying Hemiparetic Gait
Who cites it
24 citing papers in PubMed, 57 citations in OpenAlex.
- Enhanced motor learning and motor savings after acute intermittent hypoxia are associated with a reduction in metabolic cost.The Journal of physiology · 2024Trial
- Multi-objective control in human walking: insight gained through simultaneous degradation of energetic and motor regulation systems.Journal of the Royal Society, Interface · 2019Trial
- Adaptive mediolateral control during split-belt walking: Energetics of interlimb coordination and enhanced savings following acute intermittent hypoxia.Experimental physiology · 2026Article
- Quantifying human adaptation to a novel split-belt walking condition after broad experience at different belt speeds.Scientific reports · 2026Article
- Article
- Intermittent hypoxia-induced enhancements in corticospinal excitability predict gains in motor learning and metabolic efficiency.Scientific reports · 2025Article
- Behavioural energetics in human locomotion: how energy use influences how we move.The Journal of experimental biology · 2025Review
- Author response to Panza et al.The Journal of physiology · 2025Article
- Associations between asymmetry and reactive balance control during split-belt walking.Journal of biomechanics · 2024Article
- Intermittent Hypoxia-Induced Enhancements in Corticospinal Excitability Predict Gains in Motor Learning and Metabolic Efficiency.Research square · 2024Article
- Soft robotic apparel to avert freezing of gait in Parkinson's disease.Nature medicine · 2024Article
- Neuromuscular control: from a biomechanist's perspective.Frontiers in sports and active living · 2023Review
- Manual stabilization reveals a transient role for balance control during locomotor adaptation.Journal of neurophysiology · 2022Article
- Small directional treadmill perturbations induce differential gait stability adaptation.Journal of neurophysiology · 2022Article
- Humans use minimum cost movements in a whole-body task.Scientific reports · 2021Article
- Using asymmetry to your advantage: learning to acquire and accept external assistance during prolonged split-belt walking.Journal of neurophysiology · 2021Article
- Robot-Driven Locomotor Perturbations Reveal Synergy-Mediated, Context-Dependent Feedforward and Feedback Mechanisms of Adaptation.Scientific reports · 2020Article
- Asymmetric gait patterns alter the reactive control of intersegmental coordination patterns in the sagittal plane during walking.PloS one · 2020Article
- Taking advantage of external mechanical work to reduce metabolic cost: the mechanics and energetics of split-belt treadmill walking.The Journal of physiology · 2019Article
- Validity of Measurement for Trailing Limb Angle and Propulsion Force during Gait Using a Magnetic Inertial Measurement Unit.BioMed research international · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The theory that the sensorimotor system minimizes energetic cost during locomotion has long been supported by both computational models and empirical studies. However, it has yet to be determined if the behavior to which people converge when exposed to a novel perturbation during locomotion is also energetically optimal. We address this issue in the context of adaptation to walking on a split-belt treadmill, which can impose a left-right asymmetry in step lengths. In response to this asymmetry, participants gradually adjust their foot placement to adopt steps of equal length. Here, we characterized metabolic, mechanical, and perceptual estimates of energetic cost associated with a range of asymmetries to determine whether symmetry is the energetically optimal strategy for walking on a split-belt treadmill. We found that taking steps of equal length did not minimize metabolic cost or mechanical cost. In addition, perceptual estimates of cost were not sensitive to changes in asymmetry. However, symmetry was identified as the optimal strategy when energetic cost was estimated from a composite metric that combined both metabolic and mechanical costs. These results suggest that adaptation may arise from optimization of a composite estimate of effort derived from feedback about the interaction between the body and environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.