ArticleInternal medicine (Tokyo, Japan)2017
Successful Treatment with Alectinib for Choroidal Metastasis in Anaplastic Lymphoma Kinase Rearranged Non-small Cell Lung Cancer.
Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Right eye metastasis of small‑cell lung carcinoma: A case report.Experimental and therapeutic medicine · 2024Article
- Rapid vision improvement by using icotinib in a patient with bilateral choroidal metastases symmetrically from lung cancer.The clinical respiratory journal · 2023Article
- Choroidal metastasis resembling hemangioma on angiogram as initial manifestation of lung adenocarcinoma.International journal of ophthalmology · 2022Article
- Rapid resolution of choroidal metastatic tumour secondary to lung cancer following treatment with alectinib.BMJ case reports · 2021Article
- A Comprehensive Understanding of Choroidal Metastasis from Lung Cancer.OncoTargets and therapy · 2021Review
- Alectinib in the treatment of ocular metastases of ALK rearranged non small cell lung cancer: Description of 2 case reports.Medicine · 2020Article
- Isolated Rare Urethral Metastasis From Primary Lung Adenocarcinoma: Case Report and Literature Review.Frontiers in oncology · 2019Article
- Control of Intraocular Metastases ofCase reports in oncologyArticle
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Authors and funding
12 authors.
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Abstract
Choroidal metastasis is rare in cancer patients and it may cause visual disturbances that reduce their quality of life. In non-small cell lung cancer (NSCLC), targeted therapy against actionable driver mutations has gradually replaced radiotherapy as the treatment of choice for choroidal metastasis. Recently, there have been several case reports of choroidal metastasis in patients with anaplastic lymphoma kinase (ALK)-rearranged NSCLC. We herein report the case of a 40-year-old Japanese woman diagnosed with choroidal metastasis of an ALK-rearranged NSCLC who received alectinib as the first-line chemotherapy. Alectinib may be the best treatment for choroidal metastasis in patients harboring an ALK translocation because of its favorable side effect profile involving visual disturbances.
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