Evidence map›Paper›PMID 28794356›Full record

ArticleInternal medicine (Tokyo, Japan)2017

Early-onset, Severe Chronic Obstructive Pulmonary Disease with Pulmonary Hypertension that was Likely Induced by Toluene Exposure.

Konomi Kobayashi, Manabu Suzuki, Shota Yamamoto, Keisuke Ueno, Eriko Miyawaki, Ikuo Takazawa, Ayako Shiozawa, Teruhiko Sato, Masayuki Hojo, Haruhito Sugiyama

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Mendelian causes of early-onset emphysema: a review of the current literature.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Konomi KobayashiDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Manabu SuzukiDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Shota YamamotoDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Keisuke UenoDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Eriko MiyawakiDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Ikuo TakazawaDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Ayako ShiozawaDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Teruhiko SatoDivision of Pulmonary Medicine, Kohnodai Hospital, National Center for Global Health and Medicine, Japan.
Masayuki HojoDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Haruhito SugiyamaDivision of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
National Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early-onset pulmonary emphysema is uncommon and its pathogenesis is poorly defined. A 30-year-old man was admitted to our intensive care unit with severe respiratory failure. Besides smoking heavily since the 14 years of age, he had habitually inhaled organic solvents, such as toluene, in his adolescence. High-resolution computed tomography showed evident pulmonary emphysema throughout the lung fields. Based on the findings of right heart catheterization, he was diagnosed with an acute exacerbation of chronic obstructive pulmonary disease complicated with pulmonary hypertension. Heavy smoking from a young age and exposure to toluene were the suspected causes of the patient's severe pulmonary emphysema.

Indexed as

AdultHumansHypertension, PulmonaryLungMalePulmonary Disease, Chronic ObstructiveRespiratory InsufficiencySmokingTolueneTreatment OutcomeToluenechronic obstructivepulmonary diseasepulmonary hypertensionright-sided heart failuresevere early-onsettoluene

Identifiers

PMID28794356
PMCPMC5635309
OpenAlexW2743658197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.