Evidence map›Paper›PMID 28794231›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Cutting Edge: Murine NK Cells Degranulate and Retain Cytotoxic Function without Store-Operated Calcium Entry.

Jacquelyn Freund-Brown, Ruth Choa, Brenal K Singh, Tanner Ford Robertson, Gabrielle M Ferry, Eric Viver, Hamid Bassiri, Janis K Burkhardt, Taku Kambayashi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jacquelyn Freund-BrownDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Ruth ChoaDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0002-4798-7565
Brenal K SinghDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0003-1275-0434
Tanner Ford RobertsonDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia Research Institute, Philadelphia, PA 19104.ORCID 0000-0003-4336-3760
Gabrielle M FerryDivision of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104; and.ORCID 0000-0002-0203-9326
Eric ViverCentre d'Immunologie de Marseille-Luminy, Aix-Marseille Université, CNRS, INSERM, 13288 Marseille, France.ORCID 0000-0001-7022-8287
Hamid BassiriDivision of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104; and.
Janis K BurkhardtDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia Research Institute, Philadelphia, PA 19104.
Taku KambayashiDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; taku.kambayashi@uphs.upenn.edu.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · USCentre d’Immunologie de Marseille-Luminy · FR

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007170 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BRASS, LAWRENCE F · 1985 to 2022
$54.0M
HEMATOLOGY CLINICAL RESEARCH TRAINING PROGRAMT32HL007439 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LAWRENCE F BRASS, PETER S KLEIN · 1985 to 2026
$17.1M
Graduate Training in Developmental BiologyT32HD083185 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Michael Granato, Foteini Mourkioti · 2015 to 2026
$4.0M
The role of the T cell receptor in regulatory T cell homeostasis and expansionR01HL111501 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KAMBAYASHI, TAKU · 2012 to 2020
$3.6M
IL-33 Blockade as a Novel Therapeutic for T-cell Mediated Hypercytokinemia SyndromesR01AI121250 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI BEHRENS, EDWARD M, KAMBAYASHI, TAKU · 2016 to 2020
$3.0M
Proximal signaling complexes in NK cell effector function and developmentR01HL107589 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KAMBAYASHI, TAKU · 2011 to 2015
$2.0M
Separation of GVHD and GVT effects by a TCR signaling mutationR21AI117282 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI JORDAN, MARTHA S, KAMBAYASHI, TAKU · 2015 to 2016
$440k
The role of CAR-expressing Tregs on antigen-specific immune suppressionF31HL134325 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI SINGH, BRENAL · 2016 to 2018
$125k
NHLBI NIH HHS F31 HL134325NHLBI NIH HHS R01 HL107589NHLBI NIH HHS R01 HL111501NHLBI NIH HHS T32 HL007439NIAID NIH HHS R01 AI121250NIAID NIH HHS R21 AI117282NICHD NIH HHS T32 HD083185
6 · The paper itself

Abstract

Sustained Ca

Identifiers

PMID28794231
PMCPMC5807242
OpenAlexW2744465214

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.