Evidence map›Paper›PMID 28794154›Full record

ArticleThe Journal of biological chemistry2017

Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice.

Naresh C Bal, Sushant Singh, Felipe C G Reis, Santosh K Maurya, Sunil Pani, Leslie A Rowland, Muthu Periasamy

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it, 139 citations in OpenAlex.

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  15. Sleep deprivation stimulates adaptive thermogenesis by activating AMPK pathway in mice.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Naresh C BalFrom the School of Biotechnology, KIIT University, Bhubaneswar, Odisha 751024, India, naresh.bal@kiitbiotech.ac.in.
Sushant Singhthe Department of Physiology and Cell Biology, College of Medicine, Ohio State University, Columbus, Ohio 43210, and.
Felipe C G Reisthe Sanford Burnham Prebys Medical Discovery Institute at Lake Nona, Orlando, Florida 32827.
Santosh K Mauryathe Department of Physiology and Cell Biology, College of Medicine, Ohio State University, Columbus, Ohio 43210, and.
Sunil PaniFrom the School of Biotechnology, KIIT University, Bhubaneswar, Odisha 751024, India.
Leslie A Rowlandthe Department of Physiology and Cell Biology, College of Medicine, Ohio State University, Columbus, Ohio 43210, and.
Muthu Periasamythe Department of Physiology and Cell Biology, College of Medicine, Ohio State University, Columbus, Ohio 43210, and mperiasamy@sbpdiscovery.org.
The Ohio State University · USSanford Burnham Prebys Medical Discovery Institute · USKIIT University · IN

Funding

RECRUITMENT OF SKELETAL MUSCLE BASED ON NON-SHIVERING THERMOGENESIS IN HEALTH AND DISEASER01DK098240 · NIDDK · UNIVERSITY OF CENTRAL FLORIDA · PI PERIASAMY, MUTHU · 2013 to 2017
$1.9M
Mechanisms regulating SR Ca2+ ATPase in the AtriaR01HL088555 · NHLBI · OHIO STATE UNIVERSITY · PI PERIASAMY, MUTHU · 2008 to 2012
$1.9M
Identification of enhancers of energy expenditure via SLN/SERCA interactionK01DK102772 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI BAL, NARESH CHANDRA · 2015 to 2015
$123k
NHLBI NIH HHS R01 HL088555NIDDK NIH HHS K01 DK102772NIDDK NIH HHS R01 DK098240
6 · The paper itself

Abstract

Thermogenesis is an important homeostatic mechanism essential for survival and normal physiological functions in mammals. Both brown adipose tissue (BAT) (

Indexed as

Cold TemperatureAcclimatizationAdipose Tissue, BrownAnimalsMiceMice, KnockoutMitochondria, MuscleMuscle ProteinsMuscle, SkeletalProteolipidsThermogenesisUncoupling Protein 1Up-RegulationMuscle ProteinsProteolipidssarcolipinUcp1 protein, mouseUncoupling Protein 1adipose tissuecalcium ATPasecalcium-binding proteinskeletal muscleuncoupling protein

Identifiers

PMID28794154
PMCPMC5633124
OpenAlexW2742463962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.