Evidence map›Paper›PMID 28794047›Full record

ArticleJournal of virology2017

No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men.

Antoine Chaillon, Masato Nakazawa, Joel O Wertheim, Susan J Little, Davey M Smith, Sanjay R Mehta, Sara Gianella

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted Human Immunodeficiency Virus Type 1 Drug Resistance in a Large US Clinic Population.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Antoine ChaillonDepartment of Medicine, University of California-San Diego, La Jolla, California, USA achaillon@ucsd.edu.ORCID http://orcid.org/0000-0001-9490-3857
Masato NakazawaDepartment of Medicine, University of California-San Diego, La Jolla, California, USA.
Joel O WertheimDepartment of Medicine, University of California-San Diego, La Jolla, California, USA.
Susan J LittleDepartment of Medicine, University of California-San Diego, La Jolla, California, USA.
Davey M SmithDepartment of Medicine, University of California-San Diego, La Jolla, California, USA.
Sanjay R MehtaDepartment of Medicine, University of California-San Diego, La Jolla, California, USA.ORCID http://orcid.org/0000-0002-2028-8158
Sara GianellaDepartment of Medicine, University of California-San Diego, La Jolla, California, USA.
University of California San Diego · US

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
UCSD Department of Medicine HIV/AIDS Clinical Trials UnitUM1AI069432 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TIMOTHY J. WILKIN · 2012 to 2026
$50.4M
STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAVID J MOORE · 2001 to 2026
$50.4M
Using NK Cells to eliminate the latent HIV reservoirU19AI096113 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WOELK, CHRISTOPHER H · 2011 to 2015
$39.5M
Transmission ProbabilityP01AI074621 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2008 to 2012
$23.1M
Primary Infection Resource Consortium (PIRC)R24AI106039 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2013 to 2021
$23.1M
Southern California Primary Infection ProgramU01AI043638 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RICHMAN, DOUGLAS D · 1998 to 2010
$21.3M
San Diego Clinical and Translational Research InstituteUL1TR000100 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2012 to 2015
$19.7M
HOPE Training GrantT32AI007384 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sara Gianella Weibel, Scott L Letendre · 1990 to 2026
$9.7M
NCATS NIH HHS UL1 TR000100NIAID NIH HHS K01 AI110181NIAID NIH HHS K24 AI100665NIAID NIH HHS P01 AI074621NIAID NIH HHS P01 AI131385NIAID NIH HHS P30 AI027763NIAID NIH HHS P30 AI036214NIAID NIH HHS R21 AI134295NIAID NIH HHS R24 AI106039NIAID NIH HHS T32 AI007384NIAID NIH HHS U01 AI043638NIAID NIH HHS U01 AI068636NIAID NIH HHS U19 AI096113NIAID NIH HHS UM1 AI068636NIAID NIH HHS UM1 AI069432NICHD NIH HHS R21 HD094646NIDA NIH HHS DP1 DA034978NIMH NIH HHS P30 MH062512NIMH NIH HHS R01 MH097520NIMH NIH HHS R01 MH100974NIMH NIH HHS R01 MH101012
6 · The paper itself

Abstract

During primary HIV infection, the presence of minority drug resistance mutations (DRM) may be a consequence of sexual transmission,

Indexed as

MutationAdultAnti-HIV AgentsBiomarkersDrug Resistance, ViralHigh-Throughput Nucleotide SequencingHIV-1HIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedPhylogenyYoung AdultAnti-HIV AgentsBiomarkersBayesian hierarchical frameworkdeep sequencinghuman immunodeficiency virusminority drug resistance mutationtransmission

Identifiers

PMID28794047
PMCPMC5640831
OpenAlexW2742268575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.