ReviewMaterials (Basel, Switzerland)2015
Active Nanomaterials to Meet the Challenge of Dental Pulp Regeneration.
Review in Materials (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Application of Three Types of Scaffolds in Pulp Regeneration for Permanent Mature Teeth with Periapical Lesions: A Randomized Controlled Trial.European endodontic journal · 2024Trial
- Three-Dimensional Models of the Dental Pulp: Bridging Fundamental Biology and Regenerative Therapy.International journal of molecular sciences · 2025Review
- Applications and interventions of polymers and nanomaterials in alveolar bone regeneration and tooth dentistry.RSC advances · 2024Review
- Research Progress on Nanomaterials for Tissue Engineering in Oral Diseases.Journal of functional biomaterials · 2023Review
- Role of Nanoparticles in Environmental Remediation: An Insight into Heavy Metal Pollution from Dentistry.Bioinorganic chemistry and applications · 2022Review
- Enamel Matrix Derivative Enhances the Odontoblastic Differentiation of Dental Pulp Stem Cells via Activating MAPK Signaling Pathways.Stem cells international · 2022Article
- Nanofibrous scaffolds for regenerative endodontics treatment.Frontiers in bioengineering and biotechnology · 2022Review
- Emerging nanomaterials for dental treatments.Emerging topics in life sciences · 2020Review
- Recent Advances of Chitosan-Based Injectable Hydrogels for Bone and Dental Tissue Regeneration.Frontiers in bioengineering and biotechnology · 2020Review
- Application of Chitosan in Bone and Dental Engineering.Molecules (Basel, Switzerland) · 2019Review
- Polymer-Based Instructive Scaffolds for Endodontic Regeneration.Materials (Basel, Switzerland) · 2019Review
- Triple antibiotic paste: momentous roles and applications in endodontics: a review.Restorative dentistry & endodontics · 2018Review
- Maxillary Bone Regeneration Based on Nanoreservoirs FunctionalizedBioMed research international · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The vitality of the pulp is fundamental to the functional life of the tooth. For this aim, active and living biomaterials are required to avoid the current drastic treatment, which is the removal of all the cellular and molecular content regardless of its regenerative potential. The regeneration of the pulp tissue is the dream of many generations of dental surgeons and will revolutionize clinical practices. Recently, the potential of the regenerative medicine field suggests that it would be possible to achieve such complex regeneration. Indeed, three crucial steps are needed: the control of infection and inflammation and the regeneration of lost pulp tissues. For regenerative medicine, in particular for dental pulp regeneration, the use of nano-structured biomaterials becomes decisive. Nano-designed materials allow the concentration of many different functions in a small volume, the increase in the quality of targeting, as well as the control of cost and delivery of active molecules. Nanomaterials based on extracellular mimetic nanostructure and functionalized with multi-active therapeutics appear essential to reverse infection and inflammation and concomitantly to orchestrate pulp cell colonization and differentiation. This novel generation of nanomaterials seems very promising to meet the challenge of the complex dental pulp regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.