Evidence map›Paper›PMID 28793264›Full record

ArticleCell reports2017

Vesicle Docking Is a Key Target of Local PI(4,5)P

Chen Ji, Fan Fan, Xuelin Lou

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Optogenetic enzymes: A deep dive into design and impact.Current opinion in structural biology · 2025
    Review
  4. Article
  5. PI(4,5)PBiochimica et biophysica acta. Molecular and cell biology of lipids · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Insulin granule biogenesis and exocytosis.Cellular and molecular life sciences : CMLS · 2021
    Review
  12. Article
  13. Phosphatidylinositol 4,5-bisphosphate in the Control of Membrane Trafficking.International journal of biological sciences · 2020
    Review
  14. Cdk5-mediated phosphorylation regulates phosphatidylinositol 4-phosphate 5-kinase type I γ 90 activity and cell invasion.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chen JiDepartment of Neuroscience, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Fan FanDepartment of Neuroscience, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Xuelin LouDepartment of Neuroscience, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA. Electronic address: xlou3@wisc.edu.
University of Wisconsin–Madison · US

Funding

Regulated exocytosis and endocytosis coupling in pancreatic endocrine cellsR01DK093953 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LOU, XUELIN · 2011 to 2015
$1.6M
Exocytosis-endocytosis coupling at presynaptic terminalsR21NS101584 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI LOU, XUELIN · 2017 to 2018
$416k
NIDDK NIH HHS R01 DK093953NINDS NIH HHS R21 NS101584
6 · The paper itself

Abstract

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P

Indexed as

Secretory PathwayAnimalsCalcium SignalingCell LineCell MembraneInsulinInsulin-Secreting CellsPhosphatidylinositol 4,5-DiphosphateRatsSecretory VesiclesSyntaxin 1InsulinPhosphatidylinositol 4,5-DiphosphateSyntaxin 1Ca(2+) signaldense core vesiclesdockingexocytosisinsulin secretionlive-cell imagingoptogeneticsPI(4,5)P(2) lipid signalingTIRFM

Identifiers

PMID28793264
PMCPMC5613661
OpenAlexW2742837901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.