Evidence map›Paper›PMID 28793249›Full record

ArticleStem cell reports2017

Network-Based Genomic Analysis of Human Oligodendrocyte Progenitor Differentiation.

Suyog U Pol, Jessie J Polanco, Richard A Seidman, Melanie A O'Bara, Hani J Shayya, Karen C Dietz, Fraser J Sim

Open access · goldAbstract read
In one paragraph

Article in Stem cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Conditional Deletion ofInternational journal of molecular sciences · 2023
    Article
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  7. Identification ofPharmacogenomics and personalized medicine · 2022
    Article
  8. Article
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  10. Article
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Suyog U PolNeuroscience Program, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA; Department of Biomedical Engineering, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA.
Jessie J PolancoNeuroscience Program, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA.
Richard A SeidmanNeuroscience Program, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA.
Melanie A O'BaraDepartment of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA.
Hani J ShayyaDepartment of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA.
Karen C DietzDepartment of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA; Neuroscience Program, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA.
Fraser J SimDepartment of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA; Neuroscience Program, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo NY, USA. Electronic address: fjsim@buffalo.edu.
University at Buffalo, State University of New York · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Enabling Access to Cutting-Edge Biomedical and Behavioral ScienceR25GM095459 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI DUBOCOVICH, MARGARITA L · 2012 to 2021
$4.4M
NCATS NIH HHS UL1 TR001412NCI NIH HHS P30 CA016056NIGMS NIH HHS R25 GM095459
6 · The paper itself

Abstract

Impaired human oligodendrocyte progenitor cell (hOPC) differentiation likely contributes to failed remyelination in multiple sclerosis. The characterization of molecular pathways that regulate hOPC differentiation will provide means to induce remyelination. In this study, we determined the gene expression profile of PDGFαR

Indexed as

Gene Expression RegulationGene Regulatory NetworksGenomicsAnimalsAxonsCell DifferentiationComputational BiologyGene Expression ProfilingGTP-Binding Protein beta SubunitsHumansOligodendrocyte Precursor CellsOligodendrogliaReceptors, G-Protein-CoupledRodentiaSignal TransductionTranscriptomeGNB4 protein, humanGTP-Binding Protein beta SubunitsReceptors, G-Protein-Coupledoligodendrocyte progenitorspecies conservation

Identifiers

PMID28793249
PMCPMC5550273
OpenAlexW2744815427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.