ReviewRevista do Instituto de Medicina Tropical de Sao Paulo2017
Kidney involvement in malaria: an update.
Review in Revista do Instituto de Medicina Tropical de Sao Paulo, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.
- Clinical characteristics and outcome of malaria-associated acute kidney injury in adult patients: a systematic review and meta analysis.Malaria journal · 2026Pooled it
- Infection-associated acute kidney injury in resource-limited settings.Nature reviews. Nephrology · 2026Review
- Hidden hematological, biochemical and immune costs of asymptomatic malaria infections in semi-wild chimpanzees.PLoS pathogens · 2026Article
- Prevalence of acute kidney injury and its associated factors among malaria patients admitted to public hospitals in the Ilu Aba Bora and Bedelle Zones of Oromia region, Southwest Ethiopia.BMC infectious diseases · 2026Article
- Article
- The global epidemiology of acute kidney injury: challenges and opportunities.Nature reviews. Nephrology · 2026Review
- Plasmodium malariae is an overlooked malaria parasite with emerging challenges.Communications medicine · 2026Review
- Malaria-Associated Acute Kidney Injury in a Low-Endemic Region: A Case Series of Five ImportedCase reports in infectious diseases · 2026Article
- Malaria-Associated Acute Kidney Injury: A Key Driver of Mortality in Endemic Regions.International journal of nephrology and renovascular disease · 2026Review
- Hepatorenal protective role of encapsulatedJournal of advanced veterinary and animal research · 2026Article
- Diagnostic Concordance and Misclassification of Pre-Eclampsia in a Malaria-Endemic Setting: A Comparative Cross-Sectional Study.BioMed research international · 2026Article
- Hidden hematological, biochemical and immune costs of asymptomatic malaria infections in semi-wild chimpanzees.bioRxiv : the preprint server for biology · 2025Article
- Malaria-induced dysregulation of selected micronutrients (Ca, Mg, Na, K, Zn, Fe, Co) and plasma free amino acids; implications for pathogenesis and host immunity in a Nigerian population.Parasite epidemiology and control · 2025Article
- Malaria: past, present, and future.Signal transduction and targeted therapy · 2025Review
- Animal Models of Malaria-Associated Acute Kidney Injury.Seminars in nephrology · 2025Review
- The most lethal human protozoan parasite is plasmodium falciparum: severe malaria-associated acute renal failure - a case report.Annals of medicine and surgery (2012) · 2024Article
- Elucidation of the Active Agents in a West African Ground Herbal Medicine Formulation That Elicit Antimalarial Activities in In Vitro and In Vivo Models.Molecules (Basel, Switzerland) · 2024Article
- Clinical characteristics and outcomes of patients on haemodialysis at Jimma medical center, Ethiopia: a 7-Year review.BMC nephrology · 2024Article
- Kidney involvement in Plasmodium falciparum infection in a pregnant patient.Malaria journal · 2024Article
- A Severe Case ofLife (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malaria is an infectious disease of great importance for Public Health, as it is the most prevalent endemic disease in the world, affecting millions of people living in tropical areas of the globe. Kidney involvement is relatively frequent in infections by P. falciparum and P. malariae, but has also been described in the infection by P. vivax. Kidney complications in malaria mainly occur due to hemodynamic dysfunction and immune response. Liver complications leading to hepatomegaly, jaundice and hepatic dysfunction can also contribute to the occurrence of acute kidney injury. Histologic studies in malaria also evidence glomerulonephritis, acute tubular necrosis and acute interstitial nephritis. It is also possible to find chronic kidney disease associated with malaria, mainly in those patients suffering from repeated episodes of infection. Plasmodium antigens have already been detected in the glomeruli, suggesting a direct effect of the parasite in the kidney, which can trigger an inflammatory process leading to different types of glomerulonephritis. Clinical manifestations of kidney involvement in malaria include proteinuria, microalbuminuria and urinary casts, reported in 20 to 50% of cases. Nephrotic syndrome has also been described in the infection by P. falciparum, but it is rare. This paper highlights the main aspects of kidney involvement in malaria and important findings of the most recent research addressing this issue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.