ArticleNature2017
m
Open access · greenAbstract read
In one paragraph
Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 651 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
651citing papers in PubMed, 1 pooled it
22.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
651 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,025 citations in OpenAlex.
- Revisiting down syndrome through the lens of interferonopathy and innate immune dysregulation.Frontiers in immunology · 2026Pooled it
- Molecular functions, cellular responses and pathological implications of the RNA modification NNature reviews. Molecular cell biology · 2026Review
- A systematic transcriptomic atlas and predictive framework for metabolite-driven T cell state transitions.iScience · 2026Article
- METTL3 promotes neutrophil extracellular trap formation via SYK/ERK/MEK signaling during acute lung injury.Journal of advanced research · 2026Article
- RNA mActa pharmacologica Sinica · 2026Review
- Epigenetic training licenses naïve CD8Science advances · 2026Article
- METTL7A-Dependent mMedComm · 2026Article
- Review
- Article
- Toward A Pre-disease State-centered New Paradigm in Multi-omics Research.Genomics, proteomics & bioinformatics · 2026Article
- Targeting mNature communications · 2026Article
- mNature reviews. Neuroscience · 2026Review
- METTL14-mediated mCell death & disease · 2026Article
- METTL14 Declines Th17/Treg Ratio Via the m6A Modification of DUSP23 to Alleviate Systemic Lupus Erythematosus.Inflammation · 2026Article
- RNA modifications in cancer: regulators of tumor evolution and therapeutic response.Molecular cancer · 2026Review
- Review
- Insights from adaptive immune regulation for disease resistance breeding in livestock and poultry.Science China. Life sciences · 2026Review
- SuppressedInternational journal of molecular sciences · 2026Article
- The Role of NMedComm · 2026Review
- Trub1-mediated pseudouridylation is dispensable for immune cell development and homeostasis.Genes and immunity · 2026Article
591 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
18 authors at 4 institutions in 2 countries.
Hua-Bing LiDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Jiyu TongDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Shu ZhuDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Pedro J BatistaCenter for Dynamic Regulomes, Stanford University, Stanford, California 94305, USA.
Erin E DuffyDepartment of Molecular Biophysics &Biochemistry, Yale University, New Haven, Connecticut 06511, USA.
Jun ZhaoDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Will BailisDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Guangchao CaoDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Lina KroehlingDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Yuanyuan ChenDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Geng WangDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
James P BroughtonCenter for Dynamic Regulomes, Stanford University, Stanford, California 94305, USA.
Y Grace ChenCenter for Dynamic Regulomes, Stanford University, Stanford, California 94305, USA.
Yuval KlugerDepartment of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Matthew D SimonDepartment of Molecular Biophysics &Biochemistry, Yale University, New Haven, Connecticut 06511, USA.
Howard Y ChangCenter for Dynamic Regulomes, Stanford University, Stanford, California 94305, USA.
Zhinan YinThe First Affiliated Hospital, Biomedical Translational Research Institute and Guangdong Province Key Laboratory of Molecular Immunology and Antibody Engineering, Jinan University, Guangzhou 510632, China.
Richard A FlavellDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Yale University · USStanford University · USFirst Affiliated Hospital of Jinan University · CNHoward Hughes Medical Institute · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MSkill Development for Diverse Scientific Careers: A New Course Predoctoral Program in Cellular and Molecular BiologyT32GM007223 · NIGMS · YALE UNIVERSITY · PI BASERGA, SUSAN J · 1985 to 2019
$31.0MSpecial EquipmentP50HG007735 · NHGRI · STANFORD UNIVERSITY · PI CHANG, HOWARD Y · 2014 to 2018
$15.2MTraining Program in Investigative HepatologyT32DK007356 · NIDDK · YALE UNIVERSITY · PI MICHAEL H NATHANSON · 1986 to 2026
$7.4MStructural Motifs in RNAR01HG004361 · NHGRI · STANFORD UNIVERSITY · PI CHANG, HOWARD Y · 2007 to 2018
$4.7MIntegrating RNAs into signaling pathways by engineering covalent RNA modificationDP2HD083992 · NICHD · YALE UNIVERSITY · PI SIMON, MATTHEW DAVID · 2014 to 2014
$2.5MEFFICIENT SPECTRAL APPROACHES FOR FINDING UNDERLYING STRUCTURES IN BIG DATAR01HG008383 · NHGRI · YALE UNIVERSITY · PI KLUGER, YUVAL · 2016 to 2018
$1.2MHoward Hughes Medical InstituteNCATS NIH HHS UL1 TR001863NHGRI NIH HHS P50 HG007735NHGRI NIH HHS R01 HG004361NHGRI NIH HHS R01 HG008383NICHD NIH HHS DP2 HD083992NIDDK NIH HHS T32 DK007356NIGMS NIH HHS T32 GM007223
Abstract
N
Indexed as
HomeostasisSignal TransductionAdenosineAdoptive TransferAnimalsCell DifferentiationCell ProliferationColitisDisease Models, AnimalDNA-Binding ProteinsFemaleInterleukin-7MaleMethylationMethyltransferasesMiceAdenosineDNA-Binding ProteinsInterleukin-7MethyltransferasesMettl3 protein, mouseN-methyladenosineRag2 protein, mouseRNA, MessengerSocs1 protein, mouseSocs3 protein, mouseSTAT5 Transcription FactorSuppressor of Cytokine Signaling 1 ProteinSuppressor of Cytokine Signaling 3 ProteinSuppressor of Cytokine Signaling Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.