Evidence map›Paper›PMID 28792671›Full record

ArticleInfluenza and other respiratory viruses2017

Characterization of influenza A(H1N1)pdm09 viruses isolated from Nepalese and Indian outbreak patients in early 2015.

Kazuya Nakamura, Masayuki Shirakura, Seiichiro Fujisaki, Noriko Kishida, David F Burke, Derek J Smith, Tomoko Kuwahara, Emi Takashita, Ikuyo Takayama, Mina Nakauchi and 8 more

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 6 countries.

Kazuya NakamuraInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0003-4113-1579
Masayuki ShirakuraInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Seiichiro FujisakiInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Noriko KishidaInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
David F BurkeCenter for Pathogen Evolution, University of Cambridge, Cambridge, UK.
Derek J SmithCenter for Pathogen Evolution, University of Cambridge, Cambridge, UK.
Tomoko KuwaharaInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Emi TakashitaInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Ikuyo TakayamaInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Mina NakauchiInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Mandeep ChadhaInfluenza group, National Institute of Virology, Indian Council of Medical Research, Pune, India.
Varsha PotdarInfluenza group, National Institute of Virology, Indian Council of Medical Research, Pune, India.
Arvind BhushanInfluenza group, National Institute of Virology, Indian Council of Medical Research, Pune, India.
Bishnu Prasad UpadhyayDepartment of Health Services, National Public Health Laboratory, Kathmandu, Nepal.
Geeta ShakyaDepartment of Health Services, National Public Health Laboratory, Kathmandu, Nepal.
Takato OdagiriInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Tsutomu KageyamaInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Shinji WatanabeInfluenza Virus Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
National Institute of Infectious Diseases · JPICMR-National Institute of Virology · INNational Public Health Laboratory · NPUniversity of Cambridge · GB

Funding

NIAID NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

We characterized influenza A(H1N1)pdm09 isolates from large-scale outbreaks that occurred in Nepal and India in early 2015. Although no specific viral features, which may have caused the outbreaks, were identified, an S84N substitution in hemagglutinin was frequently observed. Chronological phylogenetic analysis revealed that these Nepalese and Indian viruses possessing the S84N substitution constitute potential ancestors of the novel genetic subclade 6B.1 virus that spread globally in the following (2015/16) influenza season. Thus, active surveillance of circulating influenza viruses in the Southern Asia region, including Nepal and India, would be beneficial for detecting novel variant viruses prior to their worldwide spread.

Indexed as

Disease OutbreaksAmino Acid SubstitutionAsiaFemaleHemagglutinin Glycoproteins, Influenza VirusHumansIndiaInfluenza A Virus, H1N1 SubtypeInfluenza, HumanMaleNepalNeuraminidasePhylogenySequence Analysis, DNAHemagglutinin Glycoproteins, Influenza VirusNeuraminidaseIndiainfluenza A(H1N1)pdm09 virusNepaloutbreak

Identifiers

PMID28792671
PMCPMC5596518
OpenAlexW2742458454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.