Comments on the Review 'Biomarkers in acute kidney injury - pathophysiological basis and clinical performance' Acta Physiol 2017, 219, 556-574: an update on kidney localization of IGFBP7 and TIMP2.

D R Emlet, X Wen, J A Kellum

Abstract readLetterComment

In one paragraph

Article in Acta physiologica (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Effects of remote ischaemic preconditioning against acute kidney injury in cardiac surgery patients: a randomized controlled trial.Perioperative medicine (London, England) · 2025
Article
Renal Assessment in Acute Cardiorenal Syndrome.Biomolecules · 2023
Review
Burn-Induced Acute Kidney Injury-Two-Lane Road: From Molecular to Clinical Aspects.International journal of molecular sciences · 2022
Review
The predictive value of TIMP-2 and IGFBP7 for kidney failure and 30-day mortality after elective cardiac surgery.Scientific reports · 2021
Article
The effectiveness of urinary TIMP-2 and IGFBP-7 in predicting acute kidney injury in critically ill neonates.Pediatric research · 2020
Article

4 · The record

Corrections and comments

Comment on
Biomarkers in acute kidney injury - pathophysiological basis and clinical performance.2017

5 · Who and what money

Authors and funding

3 authors.

D R EmletCenter for Critical Care Nephrology, CRISMA, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

X WenCenter for Critical Care Nephrology, CRISMA, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

J A KellumCenter for Critical Care Nephrology, CRISMA, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Kidney InjuryBiomarkersHumansTissue Inhibitor of Metalloproteinase-2BiomarkersTIMP2 protein, humanTissue Inhibitor of Metalloproteinase-2

Identifiers

PMID28792670

DOI10.1111/apha.12934

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.