Evidence map›Paper›PMID 28792646›Full record

ReviewJournal of magnetic resonance imaging : JMRI2018

Clinical applications of chemical exchange saturation transfer (CEST) MRI.

Kyle M Jones, Alyssa C Pollard, Mark D Pagel

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of magnetic resonance imaging : JMRI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 1 synthesis or guideline pooled it, 274 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Ultra-low fieldCommunications chemistry · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Multimodal MR Imaging for quantification of brain lipid in mice at 9.4T.bioRxiv : the preprint server for biology · 2025
    Article
  19. Engineering clinical translation of OGSE diffusion MRI.Magnetic resonance in medicine · 2025
    Review
  20. Review

102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kyle M JonesDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona, USA.
Alyssa C PollardDepartment of Chemistry, Rice University, Houston, Texas, USA.
Mark D PagelDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona, USA.
University of Arizona · USRice University · US

Funding

SPORE in Gastrointestinal CancerP50CA095060 · NCI · UNIVERSITY OF ARIZONA · PI GERNER, EUGENE W · 2002 to 2012
$25.3M
MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCHT32HL066988 · NHLBI · UNIVERSITY OF ROCHESTER · PI GEORAS, STEVE N, O'REILLY, MICHAEL A · 2001 to 2021
$8.1M
Cardiovascular Biomedical Engineering Training GrantT32HL007955 · NHLBI · UNIVERSITY OF ARIZONA · PI BARTON, JENNIFER KEHLET · 2001 to 2020
$5.1M
Detection of in vivo enzyme activities with CEST MRIR01CA169774 · NCI · UNIVERSITY OF ARIZONA · PI CARDENAS-RODRIGUEZ, JULIO · 2012 to 2016
$2.5M
Measuring extracellular pH in pre-clinical tumor models with CEST MRIR01CA167183 · NCI · UNIVERSITY OF ARIZONA · PI PAGEL, MARK DAVID · 2012 to 2015
$1.6M
Early phase clinical trial for imaging tumor acidosis in breast cancer patients using acidoCEST MRIR01CA197029 · NCI · UNIVERSITY OF ARIZONA · PI CARDENAS-RODRIGUEZ, JULIO · 2015 to 2016
$701k
NCI NIH HHS P50 CA095060NCI NIH HHS R01 CA167183NCI NIH HHS R01 CA169774NCI NIH HHS R01 CA197029NHLBI NIH HHS T32 HL007955NHLBI NIH HHS T32 HL066988
6 · The paper itself

Abstract

Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has been developed and employed in multiple clinical imaging research centers worldwide. Selective radiofrequency (RF) saturation pulses with standard 2D and 3D MRI acquisition schemes are now routinely performed, and CEST MRI can produce semiquantitative results using magnetization transfer ratio asymmetry (MTR LEVEL OF EVIDENCE: 5 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018;47:11-27.

Indexed as

Image Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingAdultAgedAnimalsBrainBrain NeoplasmsContrast MediaDisease Models, AnimalFemaleHumansHydrogen-Ion ConcentrationImage Interpretation, Computer-AssistedLymphedemaMaleContrast MediaCESTclinical imaging applicationsMRI

Identifiers

PMID28792646
PMCPMC5821273
OpenAlexW2744561951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.