Evidence map›Paper›PMID 28792285›Full record

ArticleGlobal health action2017

Awareness and management of elevated blood pressure among human immunodeficiency virus-infected adults receiving antiretroviral therapy in urban Zambia: a call to action.

Sophie Bauer, Mwanza Wa Mwanza, Roma Chilengi, Charles B Holmes, Zude Zyambo, Hansjakob Furrer, Matthias Egger, Gilles Wandeler, Michael J Vinikoor

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Sophie Bauera Department of Infectious Diseases , Bern University Hospital, University of Bern , Bern , Switzerland.
Mwanza Wa Mwanzab Centre for Infectious Diseases Research in Zambia , Lusaka , Zambia.
Roma Chilengib Centre for Infectious Diseases Research in Zambia , Lusaka , Zambia.
Charles B Holmesb Centre for Infectious Diseases Research in Zambia , Lusaka , Zambia.
Zude Zyambob Centre for Infectious Diseases Research in Zambia , Lusaka , Zambia.
Hansjakob Furrera Department of Infectious Diseases , Bern University Hospital, University of Bern , Bern , Switzerland.ORCID http://orcid.org/0000-0002-1375-3146
Matthias Eggerd Institute of Social and Preventive Medicine , University of Bern , Bern , Switzerland.ORCID http://orcid.org/0000-0001-7462-5132
Gilles Wandelera Department of Infectious Diseases , Bern University Hospital, University of Bern , Bern , Switzerland.
Michael J Vinikoorb Centre for Infectious Diseases Research in Zambia , Lusaka , Zambia.
Centre for Infectious Disease Research in Zambia · ZMUniversity of Bern · CH

Funding

Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
Impact of antiretroviral therapy on liver fibrosis in Zambian HIV/HBV patientsK01TW009998 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VINIKOOR, MICHAEL JEFFREY · 2014 to 2017
$526k
FIC NIH HHS K01 TW009998NIAID NIH HHS U01 AI069924
6 · The paper itself

Abstract

The prevalence of high blood pressure (HBP) and hypertension (HTN), awareness of the diagnoses, and use of anti-hypertensive drugs were examined among human immunodeficiency virus (HIV)-infected individuals on antiretroviral therapy (ART) in Zambia's capital Lusaka. Within a prospective cohort based at two public sector ART clinics, BP was measured at ART initiation and every 6 months thereafter as a routine clinic procedure. Predictors of HBP (systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg) during one year on ART were analyzed using logistic regression, and the proportion with HTN (2+ episodes of HBP >3 months apart) described. A phone survey was used to understand patient awareness of HBP, use of anti-hypertensive drugs, and history of cardiovascular events (CVE; myocardial infarction or stroke). Among 896 cohort participants, 887 (99.0%) had at least one BP measurement, 98 (10.9%) had HBP, and 57 (6.4%) had HTN. Increasing age (10-year increase in age: adjusted odds ratio [AOR] = 1.50; 95% confidence interval [CI] 1.20-1.93), male sex (AOR = 2.33, 95% CI 1.43-3.80), and overweight/obesity (AOR = 4.07; 95% CI 1.94-8.53) were associated with HBP. Among 66 patients with HBP, 35 (53.0%) reported awareness of the condition, and nine (25.7%) of these reported having had a CVE. Only 14 (21.2%) of those reached reported ever taking an anti-hypertensive drug, and one (1.5%) was currently on treatment. These data suggest that major improvements are needed in the management of HBP among HIV-infected individuals in settings such as Zambia.

Indexed as

AdultAmbulatory Care FacilitiesAntihypertensive AgentsBlood Pressure DeterminationCardiovascular DiseasesFemaleHIV InfectionsHumansHypertensionMaleOdds RatioPrevalenceProspective StudiesUrban PopulationZambiaAntihypertensive AgentsAfricaantiretroviral therapyhigh blood pressureHIV/AIDSnon-communicable diseases

Identifiers

PMID28792285
PMCPMC5645688
OpenAlexW2744108305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.