ArticleMucosal immunology2018
Adjuvant selection regulates gut migration and phenotypic diversity of antigen-specific CD4
Article in Mucosal immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 53 citations in OpenAlex.
- Trial
- Mechanism underlying the regulation of gut microbiota-metabolite axis and growth/immune function in lambs by leaf-derived polysaccharides fromFrontiers in veterinary science · 2026Article
- MVA-Spike encoding the A subunit of dmLT safely enhances systemic and mucosal immune responses.Frontiers in immunology · 2026Article
- Paratuberculosis: a mucosal immunology perspective.Frontiers in immunology · 2026Review
- Tanshinone I Enhances the Pulmonary Immune Response of CD8Biomedicines · 2025Article
- Parenteral vaccination with recombinant EtpA glycoprotein impairs enterotoxigenicInfection and immunity · 2025Article
- Conserved antigens for enteric vaccines.Vaccine · 2025Review
- Effects ofFrontiers in immunology · 2025Article
- From ancient remedies to modern miracles: tracing the evolution of vaccines and their impact on public health.3 Biotech · 2024Review
- Review
- Effects ofFrontiers in pharmacology · 2024Article
- Non-mucosal vaccination strategies to enhance mucosal immunity.Vaccine insights · 2023Article
- Establishment of isotype-switched, antigen-specific B cells in multiple mucosal tissues using non-mucosal immunization.NPJ vaccines · 2023Article
- The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Article
- New-age vaccine adjuvants, their development, and future perspective.Frontiers in immunology · 2023Review
- Differential Homing Receptor Profiles of Lymphocytes Induced by Attenuated versus LiveVaccines · 2022Article
- Vaccine-induced time- and age-dependent mucosal immunity to gastrointestinal parasite infection.NPJ vaccines · 2022Article
- Towards the future exploration of mucosal mRNA vaccines against emerging viral diseases; lessons from existing next-generation mucosal vaccine strategies.NPJ vaccines · 2022Review
- Mucosal vaccines - fortifying the frontiers.Nature reviews. Immunology · 2022Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Infectious diarrheal diseases are the second leading cause of death in children under 5 years, making vaccines against these diseases a high priority. It is known that certain vaccine adjuvants, chiefly bacterial ADP-ribosylating enterotoxins, can induce mucosal antibodies when delivered parenterally. Based on this, we reasoned vaccine-specific mucosal cellular immunity could be induced via parenteral immunization with these adjuvants. Here, we show that, in contrast to the Toll-like receptor-9 agonist CpG, intradermal immunization with non-toxic double-mutant heat-labile toxin (dmLT) from enterotoxigenic Escherichia coli drove endogenous, antigen-specific CD4
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.