Evidence map›Paper›PMID 28791938›Full record

ArticleEpidemiology and infection2017

Ralstonia infection in cystic fibrosis.

H D Green, R Bright-Thomas, D T Kenna, J F Turton, N Woodford, A M Jones

Abstract read
In one paragraph

Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. A nosocomial outbreak ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
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  3. Review
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  6. Article
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  9. NovelMicrobiology spectrum · 2024
    Article
  10. Article
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  12. Clinical Manifestation ofJournal of Korean medical science · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Article
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

H D GreenUniversity Hospital of South Manchester NHS Foundation Trust, Manchester Adult Cystic Fibrosis Centre,Manchester,UK.
R Bright-ThomasUniversity Hospital of South Manchester NHS Foundation Trust, Manchester Adult Cystic Fibrosis Centre,Manchester,UK.
D T KennaAntimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Reference Unit,National Infection Service, Public Health England,London,UK.
J F TurtonAntimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Reference Unit,National Infection Service, Public Health England,London,UK.
N WoodfordAntimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Reference Unit,National Infection Service, Public Health England,London,UK.
A M JonesUniversity Hospital of South Manchester NHS Foundation Trust, Manchester Adult Cystic Fibrosis Centre,Manchester,UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine prevalence of Ralstonia spp. in cystic fibrosis patients, look for any evidence of cross infection and to describe clinical outcomes for patients infected by Ralstonia spp. Prevalence of Ralstonia spp. was calculated annually from 2008 to 2016. Pulsed-field gel electrophoresis was performed on ⩾1 sample from patients with an isolation of Ralstonia spp. between 2008 and 2016. A prospective, longitudinal observational study of adult patients was performed with 12 months follow-up from recruitment. Prevalence of Ralstonia spp. rose from 0·6% in 2008 to 2·4% in 2016. In total 12 out of 14 (86%) patients with ⩾1 isolation of Ralstonia spp. developed chronic infection. A pair and a group of three unrelated patients with epidemiological connections shared strains of Ralstonia mannitolilytica. Lung function of Ralstonia spp. infected patients was moderately to severely impaired. Prevalence of Ralstonia spp. is low but increasing. The risk of a patient developing chronic Ralstonia spp. infection following first acquisition is high and cross-infection may be possible. Whether Ralstonia spp. infection causes increased pulmonary exacerbation frequency and lung function decline needs to be evaluated in larger prospective studies.

Indexed as

AdolescentAdultComorbidityCross InfectionCystic FibrosisElectrophoresis, Gel, Pulsed-FieldEnglandFemaleGram-Negative Bacterial InfectionsHumansLongitudinal StudiesMalePrevalenceProspective StudiesRalstoniaRiskBacterial typinghospital infectionmolecular epidemiology

Identifiers

PMID28791938
PMCPMC9203427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.