ArticleFrontiers of medicine2018
Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty.
Article in Frontiers of medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- An updated meta-analysis of the relationship between vitamin D levels and precocious puberty.Frontiers in endocrinology · 2023Pooled it
- Association between vitamin D and central precocious puberty in children: Threshold effects and mediation mechanisms based on LC-MS/MS quantitation.Journal of endocrinological investigation · 2026Article
- Phenotype-specific 25-hydroxyvitamin D and fat-soluble vitamin profiles in girls with pediatric endocrine disorders: a large cross-sectional study.Frontiers in nutrition · 2026Article
- Investigation of vitamin D deficiency in girls with growth and development variations-a single center study.Frontiers in pediatrics · 2025Article
- Interaction between Vitamin D homeostasis, gut microbiota, and central precocious puberty.Frontiers in endocrinology · 2024Review
- Confirming the association between low serum 25OHD levels in girls with central precocious puberty and its severity.BMC pediatrics · 2023Article
- Association between Vitamin D Levels, Puberty Timing, and Age at Menarche.Children (Basel, Switzerland) · 2023Review
- Gut microbiome combined with metabolomics reveals biomarkers and pathways in central precocious puberty.Journal of translational medicine · 2023Article
- Serum 25-hydroxyvitamin D levels and the risk of idiopathic central precocious puberty in girls.Clinics (Sao Paulo, Brazil) · 2023Article
- Vitamin D status and parathyroid hormone assessment in girls with central precocious puberty.Journal of endocrinological investigation · 2022Article
- The clinical value of serum-related indexes in differentiating simple premature thelarche from idiopathic central precocious puberty.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between vitamin D deficiency and idiopathic central precocious puberty (ICPP) has been recently documented. In this study, 280 girls diagnosed with ICPP and 188 normal puberty control girls of similar ages were enrolled and retrospectively studied. The ICPP group had significantly lower serum 25-hydroxyvitamin D (25[OH]D) levels than the control group. Furthermore, a nonlinear relationship was found between serum 25[OH]D and ICPP, and a cut-off point for serum 25[OH]D was found at 31.8 ng/ml for ICPP with and without adjusting the different confounding factors. Girls with serum 25[OH]D ≥ 31.8 ng/ml had a lower odds ratio (unadjusted: OR 0.36, 95% CI 0.15 to 0.83, P < 0.05; height and weight adjusted: OR 0.44, 95% CI 0.18 to 1.08, P = 0.072; BMI adjusted: OR 0.36, 95% CI 0.16 to 0.84, P < 0.05). The ICPP subjects with 25[OH]D deficiency had a higher body mass index (BMI) than the subjects from the two other subgroups. Correlation analysis showed that vitamin D level is correlated with BMI and some metabolic parameters in the ICPP group. Our study suggested that vitamin D status may be associated with ICPP risk and may have a threshold effect on ICPP.
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