Evidence map›Paper›PMID 28791334›Full record

ArticleeNeuro

Normal Striatal Vesicular Acetylcholine Transporter Expression in Tourette Syndrome.

Roger L Albin, Christine Minderovic, Robert A Koeppe

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Cholinergic System Changes in Dopa-Unresponsive Freezing of Gait in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Article
  7. Cholinergic modulation of striatal microcircuits.The European journal of neuroscience · 2019
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Roger L AlbinNeurology Service and Geriatrics Research, Education, and Clinical Center, Veterans Affairs Ann Arbor Health System, Ann Arbor, MI 48105.ORCID 0000-0002-0629-608X
Christine MinderovicDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109.
Robert A KoeppeUniversity of Michigan Morris K. Udall Center, Ann Arbor, MI 41809.
University of Michigan · US

Funding

Public Outreach and Education CoreP50NS091856 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2014 to 2019
$10.1M
Cholinergic Interneurons in Tourette SyndromeR21NS088302 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2014 to 2015
$427k
NINDS NIH HHS P50 NS091856NINDS NIH HHS R21 NS088302
6 · The paper itself

Abstract

Considerable prior work suggests basal ganglia dysfunction in Tourette syndrome (TS). Analysis of a small number of postmortem specimens suggests deficits of some striatal interneuron populations, including striatal cholinergic interneurons. To assess the integrity of striatal cholinergic interneurons in TS, we used [

Indexed as

AdolescentAdultBrain MappingCorpus StriatumFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPositron-Emission TomographyRestTourette SyndromeVesicular Acetylcholine Transport ProteinsYoung AdultVesicular Acetylcholine Transport ProteinsAcetylcholineStriatumTourette SyndromeVChAT

Identifiers

PMID28791334
PMCPMC5547197
OpenAlexW2740759365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.