Evidence map›Paper›PMID 28791014›Full record

ArticleFrontiers in immunology2017

Rapid, Automated, and Specific Immunoassay to Directly Measure Matrix Metalloproteinase-9-Tissue Inhibitor of Metalloproteinase-1 Interactions in Human Plasma Using AlphaLISA Technology: A New Alternative to Classical ELISA.

Helena Pulido-Olmo, Elena Rodríguez-Sánchez, José Alberto Navarro-García, María G Barderas, Gloria Álvarez-Llamas, Julián Segura, Marisol Fernández-Alfonso, Luis M Ruilope, Gema Ruiz-Hurtado

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Helena Pulido-OlmoLaboratorio de Hipertensión y Riesgo Cardiovascular y Unidad de Hipertensión, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Madrid, Spain.
Elena Rodríguez-SánchezLaboratorio de Hipertensión y Riesgo Cardiovascular y Unidad de Hipertensión, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Madrid, Spain.
José Alberto Navarro-GarcíaLaboratorio de Hipertensión y Riesgo Cardiovascular y Unidad de Hipertensión, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Madrid, Spain.
María G BarderasLaboratorio de Fisiopatologia Vascular, Hospital Nacional de Paraplejicos SESCAM, Toledo, Spain.
Gloria Álvarez-LlamasDepartamento de Inmunologia, IIS-Fundacion Jimenez Diaz, REDinREN, Universidad Autónoma de Madrid, Madrid, Spain.
Julián SeguraLaboratorio de Hipertensión y Riesgo Cardiovascular y Unidad de Hipertensión, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Madrid, Spain.
Marisol Fernández-AlfonsoFacultad de Farmacia, Instituto Pluridisciplinar, Universidad Complutense de Madrid, Madrid, Spain.
Luis M RuilopeLaboratorio de Hipertensión y Riesgo Cardiovascular y Unidad de Hipertensión, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Madrid, Spain.
Gema Ruiz-HurtadoLaboratorio de Hipertensión y Riesgo Cardiovascular y Unidad de Hipertensión, Instituto de Investigación imas12, Hospital Universitario 12 de Octubre, Madrid, Spain.
Hospital Universitario 12 De Octubre · ESUniversidad Autónoma de Madrid · ESUniversidad Complutense de Madrid · ESServicio de Salud de Castilla La Mancha · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protocol describes a novel, rapid, and no-wash one-step immunoassay for highly sensitive and direct detection of the complexes between matrix metalloproteinases (MMPs) and their tissue inhibitor of metalloproteinases (TIMPs) based on AlphaLISA

Indexed as

AlphaLISA®immunoassaymatrix metalloproteinase-9protein interactiontissue inhibitor of metalloproteinase-1

Identifiers

PMID28791014
PMCPMC5523156
OpenAlexW2738905037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.