Evidence map›Paper›PMID 28790988›Full record

ArticleFrontiers in microbiology2017

Non-antibiotic Isotretinoin Treatment Differentially Controls

Angela E Ryan-Kewley, David R Williams, Neill Hepburn, Ronald A Dixon

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Acne and the cutaneous microbiome: A systematic review of mechanisms and implications for treatments.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Pooled it
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  8. Adult skin acute stress responses to short-term environmental and internal aggression from exposome factors.Journal of the European Academy of Dermatology and Venereology : JEADV · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Angela E Ryan-KewleySchool of Health Sciences, Manchester Metropolitan UniversityManchester, United Kingdom.
David R WilliamsJoseph Banks Laboratories, School of Life Sciences, University of LincolnLincoln, United Kingdom.
Neill HepburnDermatology Department, Lincoln County HospitalLincoln, United Kingdom.
Ronald A DixonJoseph Banks Laboratories, School of Life Sciences, University of LincolnLincoln, United Kingdom.
University of Lincoln · GBLincoln County Hospital · GBManchester Metropolitan University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emergence and potential transfer of antibiotic resistance in skin microorganisms is of current concern in medicine especially in dermatology contexts where long term treatment with antibiotics is common. Remarkably, non-antibiotic therapy in the form of isotretinoin - a non-antimicrobial retinoid is effective at reducing or eradicating the anaerobe

Indexed as

Acne vulgarisantibiotic resistanceisotretinoin treatment and Propionibacterium acnesskin microbiome

Identifiers

PMID28790988
PMCPMC5524737
OpenAlexW2729343635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.