Evidence map›Paper›PMID 28790959›Full record

ArticleFrontiers in psychology2017

Brain Processing of Contagious Itch in Patients with Atopic Dermatitis.

Christina Schut, Hideki Mochizuki, Shoshana K Grossman, Andrew C Lin, Christopher J Conklin, Feroze B Mohamed, Uwe Gieler, Joerg Kupfer, Gil Yosipovitch

Abstract read
In one paragraph

Article in Frontiers in psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Central neural circuits underlying itch sensation.Nature reviews. Neuroscience · 2025
    Review
  4. Review
  5. Article
  6. The Psychology of Atopic Dermatitis.Journal of clinical medicine · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Functional Magnetic Resonance Imaging and Applications in Dermatology.JID innovations : skin science from molecules to population health · 2021
    Article
  12. Article
  13. Itch Matrixes.Frontiers in medicine · 2021
    Article
  14. Article
  15. What is new in the psychology of chronic itch?Experimental dermatology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christina SchutInstitute of Medical Psychology, Justus-Liebig-UniversityGiessen, Germany.
Hideki MochizukiDepartment of Dermatology, Lewis Katz School of Medicine at Temple University, PhiladelphiaPA, United States.
Shoshana K GrossmanDepartment of Dermatology, Lewis Katz School of Medicine at Temple University, PhiladelphiaPA, United States.
Andrew C LinDepartment of Dermatology, Lewis Katz School of Medicine at Temple University, PhiladelphiaPA, United States.
Christopher J ConklinDepartment of Radiology, Jefferson Integrated Magnetic Resonance Imaging Center, Thomas Jefferson University, PhiladelphiaPA, United States.
Feroze B MohamedDepartment of Radiology, Jefferson Integrated Magnetic Resonance Imaging Center, Thomas Jefferson University, PhiladelphiaPA, United States.
Uwe GielerDepartment of Dermatology, University Hospital of Giessen and MarburgGiessen, Germany.
Joerg KupferInstitute of Medical Psychology, Justus-Liebig-UniversityGiessen, Germany.
Gil YosipovitchDepartment of Dermatology and Cutaneous Surgery and Miami Itch Center, Miller School of Medicine, University of Miami, MiamiFL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies show that itch and scratching cannot only be induced by pruritogens like histamine or cowhage, but also by the presentation of certain (audio-) visual stimuli like pictures on crawling insects or videos showing other people scratching. This phenomenon is coined "Contagious itch" (CI). Due to the fact that CI is more profound in patients with the chronic itchy skin disease atopic dermatitis (AD), we believe that it is highly relevant to study brain processing of CI in this group. Knowledge on brain areas involved in CI in AD-patients can provide us with useful hints regarding non-invasive treatments that AD-patients could profit from when they are confronted with itch-inducing situations in daily life. Therefore, this study investigated the brain processing of CI in AD-patients. 11 AD-patients underwent fMRI scans during the presentation of an itch inducing experimental video (EV) and a non-itch inducing control video (CV). Perfusion based brain activity was measured using arterial spin labeling functional MRI. As expected, the EV compared to the CV led to an increase in itch and scratching (

Indexed as

atopic dermatitiscontagious itchfunctional MRIorbitofrontal cortexstriatumsupplementary motor area

Identifiers

PMID28790959
PMCPMC5524890

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.