Evidence map›Paper›PMID 28790826›Full record

ArticleNeuropsychiatric disease and treatment2017

Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder.

Jianbo Lai, Qiaoqiao Lu, Tingting Huang, Shaohua Hu, Yi Xu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Neuropsychiatric disease and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jianbo LaiDepartment of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine.
Qiaoqiao LuDepartment of Internal Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Tingting HuangDepartment of Internal Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Shaohua HuDepartment of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine.
Yi XuDepartment of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine.
First Affiliated Hospital Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quetiapine, an atypical antipsychotic, has been extensively used in patients with bipolar disorder. Overdose of quetiapine can result in severe complications, such as coma, seizure, respiratory depression, arrhythmia, and even death. However, the paucity of toxicological evaluation in adolescence causes more potential risks in this population. Herein, we present a case of hypotension and convulsive syncope after exposure to a small dose of quetiapine in a 16-year-old who was diagnosed with bipolar disorder. After cessation of quetiapine, no additional convulsive movements were reported. This case indicates that even in young patients without predisposing factors, close monitoring of adverse effects should be warranted for safety concerns, especially at the initiation of quetiapine treatment.

Indexed as

bipolar disorderconvulsive syncopehypotensionquetiapine

Identifiers

PMID28790826
PMCPMC5529712
OpenAlexW2738546460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.