ArticleInternational journal of chronic obstructive pulmonary disease2017
Asynchrony in respiratory movements between the pulmonary lobes in patients with COPD: continuous measurement of lung density by 4-dimensional dynamic-ventilation CT.
Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 32 citations in OpenAlex.
- Impaired lung deformation during expiration in chronic obstructive pulmonary disease using four-dimensional dynamic-ventilation CT.Quantitative imaging in medicine and surgery · 2026Article
- Deep learning-based lung volume estimation with dynamic chest radiography.Journal of applied clinical medical physics · 2026Article
- 4D-CT strain analysis for biomechanical characterization of COPD in patients undergoing radiotherapy planning: an exploratory study.Frontiers in medicine · 2025Article
- Regional ventilation dynamics of electrical impedance tomography validated with four-dimensional computed tomography: single-center, prospective, observational study.Critical care (London, England) · 2024Observational
- Estimation of threshold thickness of residual normal tissue in lung dysfunction detectable by dynamic chest radiography: A virtual imaging trial.Medical physics · 2024Article
- Right main pulmonary artery distensibility on dynamic ventilation CT and its association with respiratory function.European radiology experimental · 2024Article
- Respiratory Diaphragm Motion-Based Asynchronization and Limitation Evaluation on Chronic Obstructive Pulmonary Disease.Diagnostics (Basel, Switzerland) · 2023Article
- Quantitative analyzes of the variability in airways via four-dimensional dynamic ventilation CT in patients with chronic obstructive pulmonary disease: correlation with spirometry data and severity of airflow limitation.Journal of thoracic disease · 2023Article
- Area-Detector Computed Tomography for Pulmonary Functional Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Association of Respiratory Functional Indices and Smoking with Pleural Movement and Mean Lung Density Assessed Using Four-Dimensional Dynamic-Ventilation Computed Tomography in Smokers and Patients with COPD.International journal of chronic obstructive pulmonary disease · 2023Article
- Quantitative measurements of emphysema in ultra-high resolution computed tomography using model-based iterative reconstruction in comparison to that using hybrid iterative reconstruction.Physical and engineering sciences in medicine · 2022Article
- Strain Analysis in Patients at High-Risk for COPD Using Four-Dimensional Dynamic-Ventilation CT.International journal of chronic obstructive pulmonary disease · 2022Article
- Relationship of flow-volume curve pattern on pulmonary function test with clinical and radiological features in idiopathic pulmonary fibrosis.BMC pulmonary medicine · 2020Article
- Difference in Local Lung Movement During Tidal Breathing Between COPD Patients and Asthma Patients Assessed by Four-dimensional Dynamic-ventilation CT Scan.International journal of chronic obstructive pulmonary disease · 2020Article
- Stereotactic body radiotherapy in patients with chronic obstructive pulmonary disease and interstitial pneumonia: a review.International journal of clinical oncology · 2019Review
- Influence of Emphysema and Air Trapping Heterogeneity on Pulmonary Function in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2019Article
- Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans.International journal of chronic obstructive pulmonary disease · 2019Article
- Dynamic-Ventilatory Digital Radiography in Air Flow Limitation: A Change in Lung Area Reflects Air Trapping.Respiration; international review of thoracic diseasesArticle
- Strain measurement on four-dimensional dynamic-ventilation CT: quantitative analysis of abnormal respiratory deformation of the lung in COPD.International journal of chronic obstructive pulmonary diseaseArticle
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFour-dimensional dynamic-ventilation CT imaging demonstrates continuous movement of the lung. The aim of this study was to assess the correlation between interlobar synchrony in lung density and spirometric values in COPD patients and smokers, by measuring the continuous changes in lung density during respiration on the dynamic-ventilation CT. MATERIALS AND
methodsThirty-two smokers, including ten with COPD, underwent dynamic-ventilation CT during free breathing. CT data were continuously reconstructed every 0.5 sec. Mean lung density (MLD) of the five lobes (right upper [RU], right middle [RM], right lower [RL], left upper [LU], and left lower [LL]) was continuously measured by commercially available software using a fixed volume of volume of interest which was placed and tracked on a single designated point in each lobe. Concordance between the MLD time curves of six pairs of lung lobes (RU-RL, RU-RM, RM-RL, LU-LL, RU-LU, and RL-LL lobes) was expressed by cross-correlation coefficients. The relationship between these cross-correlation coefficients and the forced expiratory volume in one second/forced vital capacity (FEV
resultsIn all six pairs of the pulmonary lobes, the cross-correlation coefficients of the two MLD curves were significantly positively correlated with FEV
conclusionThe synchrony of respiratory movements between the pulmonary lobes is limited or lost in patients with more severe airflow limitation.
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