Evidence map›Paper›PMID 28790810›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2017

Indices of iron homeostasis correlate with airway obstruction in an NHANES III cohort.

Andrew J Ghio, Elizabeth D Hilborn

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Observational
  2. Observational
  3. Review
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Smoking-induced iron dysregulation in the lung.Free radical biology & medicine · 2019
    Review
  13. Review
  14. Article
  15. Article
  16. Cigarette Smoke Particle-Induced Lung Injury and Iron Homeostasis.International journal of chronic obstructive pulmonary disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew J GhioEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, Chapel Hill, NC, USA.
Elizabeth D HilbornEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, Chapel Hill, NC, USA.
Environmental Protection Agency · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cigarette smoking results in the accumulation of iron both systemically and locally, in the lung thereby causing imbalance in iron homeostasis. This disruption in iron homeostasis can be associated with oxidative stress and consequent tissue injury. Therefore, in this study, we tested the association between iron homeostasis and airway obstruction by examining a large cohort of smokers and non-smokers for relationships between 1) serum ferritin and iron concentrations and transferrin saturation and 2) forced vital capacity (FVC), forced expiratory volume in 1 s (FEV

Indexed as

AdultAgedAged, 80 and overBiomarkersFemaleFerritinsForced Expiratory VolumeHomeostasisHumansIronLungLung Diseases, ObstructiveMaleMiddle AgedNutrition SurveysRisk FactorsBiomarkersFerritinsIronTransferrinchronic obstructive pulmonary diseaseferritinsforced expiratory volumeironrespiratory function testsspirometryvital capacity

Identifiers

PMID28790810
PMCPMC5529299
OpenAlexW2739095652

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.