Evidence map›Paper›PMID 28790670›Full record

ArticleMedical journal, Armed Forces India2000

ASTROCYTOMAS AND PROGNOSIS-FROM MORPHOLOGY TO TUMOR BIOLOGY.

Ritu Lakhtakia, Arti Trehan, Ramji Rai, S Mukherjee

Open access · bronzeAbstract read
In one paragraph

Article in Medical journal, Armed Forces India, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ritu LakhtakiaClassified Specialist (Pathology), Department of Pathology, All India Institute of Medical Sciences (AIIMS), New Delhi (on study leave).
Arti TrehanGraded Specialist (Pathology) CH (AF), Bangalore.
Ramji RaiProfessor and Head, Department of Pathology, Armed Forces Medical College, Pune 411 040.
S MukherjeeSenior Adviser (Radiology and Radiotherapy), Army Hospital (R & R), New Delhi.
All India Institute of Medical Sciences · INArmed Forces Medical College · INArmy Hospital Research and Referral · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty-seven cases of Astrocytoma were studied to assess the role of a newly introduced proliferation marker-Proliferating Cell Nuclear Antigen (PCNA) in improving prognostic accuracy in comparison to traditional histologic methods like grading. The study revealed a direct correlation between grading and PCNA expression as determined by labelling indices (LI). A 25% PCNA LI separated low and high grade tumors. The difference between PCNA LI's of patients who were alive and those who were dead at the end of the study was statistically significant. However, in this study with limited follow-up, statistically significant relation to survival and recurrence could not be established. The study introduces a new method of assessing tumor biology that enables objectivity in prediction of tumor behaviour.

Indexed as

AstrocytomaPCNAProliferation markers

Identifiers

PMID28790670
PMCPMC5531997
OpenAlexW2621858180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.