Evidence map›Paper›PMID 28790546›Full record

ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2017

Effect of Cigarette Smoking on Haematological Parameters in Healthy Population.

Maja Malenica, Besim Prnjavorac, Tamer Bego, Tanja Dujic, Sabina Semiz, Selma Skrbo, Amar Gusic, Ajla Hadzic, Adlija Causevic

Abstract read
In one paragraph

Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 2 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 2 syntheses or guidelines pooled it, 218 citations in OpenAlex.

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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Maja MalenicaDepartment for Biochemistry and Clinical Analysis, Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina (BH).
Besim PrnjavoracGeneral Hospital Tesanj, Tesanj, Bosnia and Herzegovina (BH).
Tamer BegoDepartment for Biochemistry and Clinical Analysis, Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina (BH).
Tanja DujicDepartment for Biochemistry and Clinical Analysis, Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina (BH).
Sabina SemizDepartment for Biochemistry and Clinical Analysis, Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina (BH).
Selma SkrboDepartment for Clinical Pharmacy, Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina (BH).
Amar GusicFaculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina (BH).
Ajla HadzicFaculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina (BH).
Adlija CausevicDepartment for Biochemistry and Clinical Analysis, Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina (BH).
University of Sarajevo · BAInstitute of Metrology of Bosnia and Herzegovina · BA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTobacco cigarette smoking is one of the major leading causes of death throughout the world. Smoking has both acute and chronic effect on haematological parameters. The aim of the present study was to assess the extent of adverse effects of cigarette smoking on biochemical characteristics in healthy smokers. SUBJECTS AND

methodOne hundred and fifty six subjects participated in this study, 56 smokers and 100 non-smokers. The smokers were regularly consuming 10-20 cigarettes per day for at least 3 years. Complete blood cell count was analyzed by CELL-DYN 3700 fully automatic haematological analyzer.

resultsThe smokers had significantly higher levels of white blood cell (p<0,001), hemoglobin (p=0,042), mean corpuscular volume (p=0,001) and mean corpuscular hemoglobin concentration (p<0,001). All other measured parameters did not differ significantly. Cigarette smoking caused a significant increase (p<0,001) in red blood cells, white blood cells (p=0,040), hemoglobin (p<0,001), hematocrit (p=0,047) and mean corpuscular hemoglobin (p<0,001) in males in comparison to female smokers.

conclusionIn conclusion, our study showed that continuous cigarette smoking has severe adverse effects on haematological parameters (e.g., hemoglobin, white blood cells count, mean corpuscular volume, mean corpuscular hemoglobin concentration, red blood cells count, hematocrit) and these alterations might be associated with a greater risk for developing atherosclerosis, polycythemia vera, chronic obstructive pulmonary disease and/or cardiovascular diseases.

Indexed as

AdultBlood Cell CountCigarette SmokingErythrocyte IndicesFemaleHealthy VolunteersHematocritHemoglobinsHumansLeukocytesMaleMiddle AgedSex CharacteristicsHemoglobinscigarette smokinghaematological parametershealthy population

Identifiers

PMID28790546
PMCPMC5511531
OpenAlexW2611549271

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.