Observational studyMedical archives (Sarajevo, Bosnia and Herzegovina)2017
Serum Uric Acid Could Differentiate Acute Myocardial Infarction and Unstable Angina Pectoris in Hyperuricemic Acute Coronary Syndrome Patients.
Observational study in Medical archives (Sarajevo, Bosnia and Herzegovina), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Clinical Treatment Analysis and Imaging Study of Patients with Acute Angina in Cardiovascular Medicine.Journal of healthcare engineering · 2021Trial
- New Insights into Uric Acid Metabolism in the Pathophysiology of Ischaemic Heart Disease.European cardiology · 2025Review
- Progress of uric acid in cardiovascular disease.Cardiovascular endocrinology & metabolism · 2024Review
- Uric acid is associated with increased risk of myocardial infarction: results from NHANES 2009-2018 and bidirectional two-sample Mendelian randomization analysis.Frontiers in endocrinology · 2024Article
- Monocyte to high-density lipoprotein cholesterol ratio and serum uric acid in Chinese adults: a cross-sectional study.BMC endocrine disorders · 2022Article
- Detection and Quantification of the Relationship between the Ratio of Triglycerides over High-Density Lipoprotein Cholesterol and the Level of Serum Uric Acid: One Cross-Sectional Study.International journal of endocrinology · 2022Article
- Diagnostic value and prognostic significance of CTRP9 combined with pentraxin-3 in acute coronary syndrome.Experimental and therapeutic medicine · 2021Article
- Evaluation of Preclinical and Clinical Studies Published in Medical Journals of Bosnia and Herzegovina: Methodology Issues.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020Article
- Modeling analysis of the relationship between atherosclerosis and related inflammatory factors.Saudi journal of biological sciences · 2017Article
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5 authors.
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Abstract
introductionSerum uric acid (SUA) is the final product of purine metabolism in humans.
aimThe present study aimed to identify a potential association between serum UA and cardiac troponin I (cTnI) levels and to find out whether uric acid could differentiate patients presenting with the acute myocardial infarction (AMI) and unstable angina pectoris (UAP) in hyperuricemic and normouricemic acute coronary syndrome (ACS) patients.
methodsEighty ACS patients, aged 50-83 years, were enrolled in the study, 40 of them presenting with AMI and 40 with UAP. Frequency of patients with serum uric level over threshold for hyperuricemia was investigated and two groups of patients were formed such as hyperuricemic and normouricemic groups (A and B groups, respectively) independently of type of ACS. Those groups of patients were also subjected to cTnI measurement.
resultsLevels of SUA are associated with the type of ACS in the hyperuricemic ACS patients (AMI versus UAP, 499(458-590), 425(400-447) mmol/L, p=0.007, respectively). Uric acid correlated significantly with cTnI, moderate positively in the group A (rho=0.358, p=0.038) and moderate negatively in the group B (r=-0.309, p=0.037) of ACS patients. Multiple logistic regression analysis revealed that cTnI and age were independently associated with the SUA levels in the group A of ACS patients.
conclusionsSerum uric acid differentiates AIM and UAP patients in hyperuricemic group of acute coronary syndrome. Therefore it can be used as nonspecific parameter for evaluation of the myocardial lesion extent only in hyperuricemic ACS patients. This is supported by finding that cTnI along with age predicts SUA level in hyperuricemic ACS patients.
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