Evidence map›Paper›PMID 28790431›Full record

ArticleScientific reports2017

Differentiation impairs Bach1 dependent HO-1 activation and increases sensitivity to oxidative stress in SH-SY5Y neuroblastoma cells.

Sabrina Piras, Anna Lisa Furfaro, Lorenzo Brondolo, Mario Passalacqua, Umberto Maria Marinari, Maria Adelaide Pronzato, Mariapaola Nitti

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  3. Life (Basel, Switzerland) · 2024
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  5. Selenomethionine Attenuated HAntioxidants (Basel, Switzerland) · 2023
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  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. HO-1 Limits the Efficacy of Vemurafenib/PLX4032 in BRAFAntioxidants (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sabrina PirasDepartment of Experimental Medicine, University of Genoa, Via L.B. Alberti 2, 16132, Genoa, Italy.
Anna Lisa FurfaroGiannina Gaslini Institute, Via Gerolamo Gaslini 5, 16147, Genoa, Italy.
Lorenzo BrondoloDepartment of Experimental Medicine, University of Genoa, Via L.B. Alberti 2, 16132, Genoa, Italy.
Mario PassalacquaDepartment of Experimental Medicine, University of Genoa, Via L.B. Alberti 2, 16132, Genoa, Italy.ORCID 0000-0003-2779-6259
Umberto Maria MarinariDepartment of Experimental Medicine, University of Genoa, Via L.B. Alberti 2, 16132, Genoa, Italy.
Maria Adelaide PronzatoDepartment of Experimental Medicine, University of Genoa, Via L.B. Alberti 2, 16132, Genoa, Italy.
Mariapaola NittiDepartment of Experimental Medicine, University of Genoa, Via L.B. Alberti 2, 16132, Genoa, Italy. Mariapaola.Nitti@unige.it.
University of Genoa · ITIstituto Giannina Gaslini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuronal adaptation to oxidative stress is crucially important in order to prevent degenerative diseases. The role played by the Nrf2/HO-1 system in favoring cell survival of neuroblastoma (NB) cells exposed to hydrogen peroxide (H

Indexed as

Cell DifferentiationOxidative StressBasic-Leucine Zipper Transcription FactorsCell Line, TumorCell SurvivalHeme Oxygenase-1HumansHydrogen PeroxideNeuronsOxidantsBACH1 protein, humanBasic-Leucine Zipper Transcription FactorsHeme Oxygenase-1HMOX1 protein, humanHydrogen PeroxideOxidants

Identifiers

PMID28790431
PMCPMC5548785
OpenAlexW2741243244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.