Evidence map›Paper›PMID 28790360›Full record

ArticleScientific reports2017

Comprehensive validation of T- and B-cell deficiency in rag1-null zebrafish: Implication for the robust innate defense mechanisms of teleosts.

Yumie Tokunaga, Masamichi Shirouzu, Ryota Sugahara, Yasutoshi Yoshiura, Ikunari Kiryu, Mitsuru Ototake, Takahiro Nagasawa, Tomonori Somamoto, Miki Nakao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Generation of IgMScientific reports · 2025
    Article
  4. Article
  5. Article
  6. Tipping the Scales With Zebrafish to Understand Adaptive Tumor Immunity.Frontiers in cell and developmental biology · 2021
    Review
  7. Article
  8. Review
  9. Evidence of Trained Immunity in a Fish: Conserved Features in Carp Macrophages.Journal of immunology (Baltimore, Md. : 1950) · 2019
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yumie TokunagaLaboratory of Marine Biochemistry, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, 812-8581, Japan.
Masamichi ShirouzuLaboratory of Marine Biochemistry, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, 812-8581, Japan.
Ryota SugaharaLaboratory of Marine Biochemistry, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, 812-8581, Japan.
Yasutoshi YoshiuraYashima station, Stock Enhancement and Management Department, National Research Institute of Fisheries and Enhancement of Inland Sea, Japan Fisheries Research and Education Agency, 243 Yashima-higashi, Takamatsu, Kagawa, 761-0111, Japan.
Ikunari KiryuNational Research Institute of Aquaculture, Fisheries Research Agency, Tamaki, Mie, 519-0423, Japan.
Mitsuru OtotakeNational Research Institute of Aquaculture, Fisheries Research Agency, Tamaki, Mie, 519-0423, Japan.
Takahiro NagasawaLaboratory of Marine Biochemistry, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, 812-8581, Japan.
Tomonori SomamotoLaboratory of Marine Biochemistry, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, 812-8581, Japan. somamoto@agr.kyushu-u.ac.jp.
Miki NakaoLaboratory of Marine Biochemistry, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, 812-8581, Japan.
Kyushu University · JPJapan Fisheries Research and Education Agency · JPUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rag1

Indexed as

Adaptive ImmunityAnimalsB-LymphocytesDisease ResistanceFish DiseasesHepatopancreasHomeodomain ProteinsHomeostasisHumansImmunity, InnateMiceSpleenT-LymphocytesZebrafishHomeodomain ProteinsRAG-1 protein

Identifiers

PMID28790360
PMCPMC5548773
OpenAlexW2740912529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.