ArticleScientific reports2017
3D printed personalized titanium plates improve clinical outcome in microwave ablation of bone tumors around the knee.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Biomechanical performance of proximal tibia fracture plates: A review.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026Review
- Patient-Specific 3-Dimensional-Printed Orthopedic Implants and Surgical Devices Are Potential Alternatives to Conventional Technology But Require Additional Characterization.Clinics in orthopedic surgery · 2025Review
- Three-Dimensional Bioprinting: A Comprehensive Review for Applications in Tissue Engineering and Regenerative Medicine.Bioengineering (Basel, Switzerland) · 2024Review
- Biomedical Applications of Titanium Alloys: A Comprehensive Review.Materials (Basel, Switzerland) · 2023Review
- Design considerations for patient-specific bone fixation plates: a literature review.Medical & biological engineering & computing · 2023Review
- Three-Dimensional Printing Bioceramic Scaffolds Using Direct-Ink-Writing for Craniomaxillofacial Bone Regeneration.Tissue engineering. Part C, Methods · 2023Review
- An overview of 3D printed metal implants in orthopedic applications: Present and future perspectives.Heliyon · 2023Review
- Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study.BMC cancer · 2022Article
- Feasibility study of three-dimensional printing knee model using the ultra-low-dose CT scan for preoperative planning and simulated surgery.Insights into imaging · 2022Article
- 3D printing guide plate for accurate hemicortical bone tumor resection in metaphysis of distal femoral: a technical note.Journal of orthopaedic surgery and research · 2021Article
- Review of a new bone tumor therapy strategy based on bifunctional biomaterials.Bone research · 2021Review
- Personalized Three-Dimensional Printed Anterior Titanium Plate to Treat Double-Column Acetabular Fractures: A Retrospective Case-Control Study.Orthopaedic surgery · 2020Article
- Clinical Guideline for Microwave Ablation of Bone Tumors in Extremities.Orthopaedic surgery · 2020Article
- 3D printing in shoulder surgery.Orthopedic reviews · 2020Article
- Opportunities and challenges of translational 3D bioprinting.Nature biomedical engineering · 2020Review
- Use of three-dimensional printing in preoperative planning in orthopaedic trauma surgery: A systematic review and meta-analysis.World journal of orthopedics · 2020Article
- Application of 3D-printed Customized Guides in Subtalar Joint Arthrodesis.Orthopaedic surgery · 2019Article
- Clinical feasibility and application value of computer virtual reduction combined with 3D printing technique in complex acetabular fractures.Experimental and therapeutic medicine · 2019Article
- Photothermal transforming agent and chemotherapeutic co-loaded electrospun nanofibers for tumor treatment.International journal of nanomedicine · 2019Article
- Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios.3D printing in medicine · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microwave ablation has been widely accepted in treating bone tumor. However, its procedure is time-consuming and usually results in postoperative fractures. To solve this problem, we designed and fabricated titanium plates customized to the patients' bone structures. The personalized titanium plates were then used for fixation after the removal of tumorous tissue. Specifically, 3D models of tumor-bearing bone segments were constructed by using computed tomography (CT) and magnetic resonance imaging (MRI). The 3D models were used to design the personalized titanium plates. The plate model was transferred into a numerical control machine for manufacturing the personalized titanium plates by 3D printing. The plates were then surgically implanted for reconstruction assistance following microwave-induced hyperthermia to remove the bone tumor. Implementation parameters and knee functions were then evaluated. No postoperative fractures, implant failures or loosening problems occurred; mean Musculoskeletal Tumor Society score was 27.17 from the latest follow-up. Mean maximum flexion of affected knees was 114.08°. The results of knee gait analysis were comparable with normal population data. Our work suggests that personalized titanium plates can significantly improve the clinical outcomes in the surgical removal of bone tumor. This study represents the first-time effort in using personalized titanium plates for such surgery.
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