Evidence map›Paper›PMID 28790311›Full record

Trial reportNature communications2017

Plasmonic silver nanoshells for drug and metabolite detection.

Lin Huang, Jingjing Wan, Xiang Wei, Yu Liu, Jingyi Huang, Xuming Sun, Ru Zhang, Deepanjali D Gurav, Vadanasundari Vedarethinam, Yan Li and 2 more

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 206 citations in OpenAlex.

  1. Observational
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  3. Review
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  6. Review
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  8. Article
  9. Fast Label-Free Metabolic Profile Recognition Identifies Phenylketonuria and Subtypes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
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  19. Article
  20. TiAnalytical and bioanalytical chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Lin HuangSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Jingjing WanDepartment of Chemistry, Shanghai University, Shanghai, 200444, People's Republic of China.
Xiang WeiSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Yu LiuSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Jingyi HuangSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Xuming SunSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Ru ZhangSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Deepanjali D GuravSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Vadanasundari VedarethinamSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Yan LiInstitute of Biophysics Key Laboratory of Interdisciplinary Research, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Ruoping ChenSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China. rubinchen@126.com.
Kun QianSchool of Biomedical Engineering, Children's Hospital of Shanghai, and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China. k.qian@sjtu.edu.cn.
Shanghai Children's Hospital · CNShanghai Jiao Tong University · CNInstitute of Biophysics · CNShanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In-vitro metabolite and drug detection rely on designed materials-based analytical platforms, which are universally used in biomedical research and clinical practice. However, metabolic analysis in bio-samples needs tedious sample preparation, due to the sample complexity and low molecular abundance. A further challenge is to construct diagnostic tools. Herein, we developed a platform using silver nanoshells. We synthesized SiO

Indexed as

Clinical Laboratory TechniquesSilverBrain DiseasesGlucoseHumansInfectionsNanoshellsPharmaceutical PreparationsPharmacokineticsPostoperative ComplicationsGlucosePharmaceutical PreparationsSilver

Identifiers

PMID28790311
PMCPMC5548796
OpenAlexW2740820047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.