Evidence map›Paper›PMID 28790187›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging.

Özden Baltekin, Alexis Boucharin, Eva Tano, Dan I Andersson, Johan Elf

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 177 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
177citing papers in PubMed, 1 pooled it
25.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

177 citing papers in PubMed, 1 synthesis or guideline pooled it, 415 citations in OpenAlex.

  1. Pooled it
  2. Article
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  7. Article
  8. Point of care antimicrobial susceptibility testing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  9. Article
  10. Article
  11. Molecular kinetics dictate population dynamics in CRISPR-based plasmid defense.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  12. Article
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  18. Review
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117 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Özden BaltekinDepartment of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, SE-751 24 Uppsala, Sweden.
Alexis BoucharinDepartment of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, SE-751 24 Uppsala, Sweden.
Eva TanoDepartment of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.
Dan I AnderssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Johan ElfDepartment of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, SE-751 24 Uppsala, Sweden; johan.elf@icm.uu.se.
Uppsala University · SEScience for Life Laboratory · SE

Funding

European Research Council 616047
6 · The paper itself

Abstract

The emergence and spread of antibiotic-resistant bacteria are aggravated by incorrect prescription and use of antibiotics. A core problem is that there is no sufficiently fast diagnostic test to guide correct antibiotic prescription at the point of care. Here, we investigate if it is possible to develop a point-of-care susceptibility test for urinary tract infection, a disease that 100 million women suffer from annually and that exhibits widespread antibiotic resistance. We capture bacterial cells directly from samples with low bacterial counts (10

Indexed as

Anti-Bacterial AgentsCiprofloxacinDrug Resistance, MicrobialEscherichia coli InfectionsFemaleHumansMicrobial Sensitivity TestsPoint-of-Care TestingReproducibility of ResultsSingle-Cell AnalysisUrinary Tract InfectionsUropathogenic Escherichia coliAnti-Bacterial AgentsCiprofloxacinantibioticASTmicrofluidicpoint of careresistanceUTI

Identifiers

PMID28790187
PMCPMC5576829
OpenAlexW2744332922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.