Evidence map›Paper›PMID 28790171›Full record

ArticleThe Journal of biological chemistry2017

The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle.

Koki Kamizaki, Ryosuke Doi, Makoto Hayashi, Takeshi Saji, Motoi Kanagawa, Tatsushi Toda, So-Ichiro Fukada, Hsin-Yi Henry Ho, Michael Eldon Greenberg, Mitsuharu Endo and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Imaging of ROR1 expression in tumors using radiolabeled affibody molecules.European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Role of the Ror family receptors in Wnt5a signaling.In vitro cellular & developmental biology. Animal · 2024
    Review
  6. Article
  7. Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1).Acta crystallographica. Section F, Structural biology communications · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Koki KamizakiFrom the Division of Cell Physiology, Department of Physiology and Cell Biology, and.
Ryosuke DoiFrom the Division of Cell Physiology, Department of Physiology and Cell Biology, and.
Makoto HayashiFrom the Division of Cell Physiology, Department of Physiology and Cell Biology, and.
Takeshi SajiFrom the Division of Cell Physiology, Department of Physiology and Cell Biology, and.
Motoi KanagawaDivision of Neurology/Molecular Brain Science, Graduate School of Medicine, Kobe University, Kobe 650-0017, Japan.
Tatsushi TodaDivision of Neurology/Molecular Brain Science, Graduate School of Medicine, Kobe University, Kobe 650-0017, Japan.
So-Ichiro Fukadathe Laboratory of Molecular and Cellular Physiology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan, and.
Hsin-Yi Henry Hothe Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115.
Michael Eldon Greenbergthe Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115.
Mitsuharu EndoFrom the Division of Cell Physiology, Department of Physiology and Cell Biology, and.
Yasuhiro MinamiFrom the Division of Cell Physiology, Department of Physiology and Cell Biology, and minami@kobe-u.ac.jp.
Harvard University · USKobe University · JPOsaka University · JP

Funding

Neurotrophic Factor Regulation of Gene ExpressionR01NS045500 · NINDS · HARVARD MEDICAL SCHOOL · PI GREENBERG, MICHAEL ELDON · 2003 to 2018
$8.2M
Deciphering Wnt-Ror signaling in cytoskeletal regulation and tissue shape controlR35GM119574 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HO, HSIN-YI HENRY · 2016 to 2021
$2.0M
NIGMS NIH HHS R35 GM119574NINDS NIH HHS R01 NS045500
6 · The paper itself

Abstract

The Ror family receptor tyrosine kinases, Ror1 and Ror2, play important roles in regulating developmental morphogenesis and tissue- and organogenesis, but their roles in tissue regeneration in adult animals remain largely unknown. In this study, we examined the expression and function of Ror1 and Ror2 during skeletal muscle regeneration. Using an

Indexed as

RegenerationAnimalsCell LineCell ProliferationGene Expression Regulation, EnzymologicInterleukin-1betaMaleMiceMice, Inbred C57BLMuscle DevelopmentMuscle, SkeletalNF-kappa BPAX7 Transcription FactorReceptor Tyrosine Kinase-like Orphan ReceptorsSatellite Cells, Skeletal MuscleSignal TransductionInterleukin-1betaNF-kappa BPax7 protein, mousePAX7 Transcription FactorReceptor Tyrosine Kinase-like Orphan ReceptorsRor1 protein, mouseRor2 protein, mouseTumor Necrosis Factor-alphacell proliferationcell signalinggene regulationgene transcriptionmuscle regenerationNF-κB (NF-KB)Ror1 receptor kinasesatellite cells (SCs)

Identifiers

PMID28790171
PMCPMC5612123
OpenAlexW2742840256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.