Evidence map›Paper›PMID 28789682›Full record

ArticleMalaria journal2017

Additional burden of asymptomatic and sub-patent malaria infections during low transmission season in forested tribal villages in Chhattisgarh, India.

Mehul Kumar Chourasia, Kamaraju Raghavendra, Rajendra M Bhatt, Dipak Kumar Swain, Hemraj M Meshram, Jayant K Meshram, Shrity Suman, Vinita Dubey, Gyanendra Singh, Kona Madhavinadha Prasad and 1 more

Abstract readComparative Study
In one paragraph

Article in Malaria journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. The impact of COVID-19 pandemic on malaria elimination.Parasite epidemiology and control · 2020
    Review
  15. COVID-19 and malaria: A symptom screening challenge for malaria endemic countries.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mehul Kumar ChourasiaNational Institute of Malaria Research (ICMR) IIR-WHO Project, Field Unit, Kondagaon, Chhattisgarh, India.
Kamaraju RaghavendraNational Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, 110077, India. kamarajur2000@yahoo.com.ORCID 0000-0002-4098-7095
Rajendra M BhattNational Institute of Malaria Research (ICMR), Field Unit, Lalpur, Raipur Chhattisgarh, India.
Dipak Kumar SwainNational Institute of Malaria Research (ICMR) IIR-WHO Project, Field Unit, Kondagaon, Chhattisgarh, India.
Hemraj M MeshramNational Institute of Malaria Research (ICMR) IIR-WHO Project, Field Unit, Kondagaon, Chhattisgarh, India.
Jayant K MeshramNational Institute of Malaria Research (ICMR) IIR-WHO Project, Field Unit, Kondagaon, Chhattisgarh, India.
Shrity SumanNational Institute of Malaria Research (ICMR) IIR-WHO Project, Field Unit, Kondagaon, Chhattisgarh, India.
Vinita DubeyNational Institute of Malaria Research (ICMR) IIR-WHO Project, Field Unit, Kondagaon, Chhattisgarh, India.
Gyanendra SinghNational Institute of Malaria Research (ICMR) IIR-WHO Project, Field Unit, Kondagaon, Chhattisgarh, India.
Kona Madhavinadha PrasadNational Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, 110077, India.
Immo KleinschmidtDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

Funding

Medical Research Council MR/K012126/1
6 · The paper itself

Abstract

backgroundThe burden of sub-patent malaria is difficult to recognize in low endemic areas due to limitation of diagnostic tools, and techniques. Polymerase chain reaction (PCR), a molecular based technique, is one of the key methods for detection of low parasite density infections. The study objective was to assess the additional burden of asymptomatic and sub-patent malaria infection among tribal populations inhabiting three endemic villages in Keshkal sub-district, Chhattisgarh, India. A cross-sectional survey was conducted in March-June 2016, during the low transmission season, to measure and compare prevalence of malaria infection using three diagnostics: rapid diagnostic test, microscopy and nested-PCR.

resultsOut of 437 individuals enrolled in the study, 103 (23.6%) were malaria positive by PCR and/or microscopy of whom 89.3% were Plasmodium falciparum cases, 77.7% were afebrile and 35.9% had sub-patent infections.

conclusionsA substantial number of asymptomatic and sub-patent malaria infections were identified in the survey. Hence, strategies for identifying and reducing the hidden burden of asymptomatic and sub-patent infections should focus on forest rural tribal areas using more sensitive molecular diagnostic methods to curtail malaria transmission.

Indexed as

AdolescentAsymptomatic InfectionsChildChild, PreschoolCross-Sectional StudiesDiagnostic Tests, RoutineFemaleHumansIndiaInfantInfant, NewbornMalariaMaleMicroscopyPolymerase Chain ReactionPrevalenceAsymptomaticChhattisgarhIndiaMalariaPCRSub-patent

Identifiers

PMID28789682
PMCPMC5549400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.